Oxymetazoline hydrochloride and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxymetazoline hydrochloride (oxymetazoline hydrochloride) and Synthroid (levothyroxine sodium). Common drug interactions include pain among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Oxymetazoline hydrochloride and Synthroid. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Oxymetazoline hydrochloride?

Oxymetazoline hydrochloride has active ingredients of oxymetazoline hydrochloride. eHealthMe is studying from 594 Oxymetazoline hydrochloride users. Check the latest studies of Oxymetazoline hydrochloride.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.

On Jul, 31, 2026

21 people who take Oxymetazoline hydrochloride and Synthroid together, and have interactions are studied.

Oxymetazoline hydrochloride and Synthroid drug interactions.

What are the common drug interactions of Oxymetazoline Hydrochloride and Synthroid, by gender? *:

female:

Pain
Abdominal pain
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Injury
Diarrhoea
Fatigue (feeling of tiredness)
Feeling hot
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Therapeutic response unexpected

male:

Anxiety
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Infusion site swelling
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Productive cough
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory tract congestion (blockage on respiratory system)

What are the common drug interactions of Oxymetazoline Hydrochloride and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Injury
Pain
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Anaphylactic reaction (serious allergic reaction)
Appendix disorder

30-39:

Anxiety
Chest discomfort
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hypersensitivity
Infusion site swelling
Panic attack
Pulmonary embolism (blockage of the main artery of the lung)
Self-injurious ideation
Stress

40-49:

Depression
Gout (uric acid crystals building up in the body)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Panic attack
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anxiety
Chronic kidney disease

50-59:

n/a

60+:

Blood bilirubin increased
Diarrhoea
Drug dependence
Fatigue (feeling of tiredness)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Skin discolouration (change of skin colour)
Weight decreased

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 19.05%
Nausea (feeling of having an urge to vomit): 4 people, 19.05%
Stress And Anxiety: 3 people, 14.29%
Menstruation Irregular: 3 people, 14.29%
Birth Control: 3 people, 14.29%
Bipolar Disorder (mood disorder): 3 people, 14.29%
Osteoporosis (bones weak and more likely to break): 2 people, 9.52%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 9.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 9.52%
Immunodeficiency Common Variable: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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