Ozempic and Fosamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Fosamax (alendronate sodium). Common drug interactions include nausea among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Fosamax. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.

On Aug, 02, 2026

23 people who take Ozempic and Fosamax together, and have interactions are studied.

What are the common drug interactions of Ozempic and Fosamax, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Weight decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depression
Infusion site erythema (reddening of the skin at infusion site)
Infusion site pruritus (severe itching at infusion site)
Decreased appetite
Memory impairment
Abdominal discomfort
Drug ineffective

male:

Back pain
Memory impairment
Cough
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
Neck pain
Pain
Pain in extremity
Renal failure (kidney dysfunction)
Tendonitis (a condition that causes pain and swelling of tendons)
Trigger finger

What are the common drug interactions of Ozempic and Fosamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Back pain
Memory impairment
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
Neck pain
Pain
Pain in extremity
Renal failure (kidney dysfunction)
Tendonitis (a condition that causes pain and swelling of tendons)
Trigger finger
Arthralgia (joint pain)

60+:

Abdominal distension
Alopecia (absence of hair from areas of the body)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fungal skin infection
Glycosylated haemoglobin increased
Kidney infection
Limb discomfort (discomfort in leg)
Nasopharyngitis (inflammation of the nasopharynx)
Pyrexia (fever)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 30.43%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 30.43%
Immunodeficiency Common Variable: 4 people, 17.39%
Blood Glucose Abnormal: 4 people, 17.39%
Joint Pain: 4 people, 17.39%
Essential Hypertension (primary hypertension): 3 people, 13.04%
Blood Glucose Increased: 3 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 13.04%
Drowsiness: 3 people, 13.04%
Sleep Disorder: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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