Ozempic and Metaxalone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Metaxalone (metaxalone). Common drug interactions include dysphonia among females and atrioventricular block complete among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Metaxalone. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

On Jul, 19, 2026

13 people who take Ozempic and Metaxalone together, and have interactions are studied.

Ozempic and Metaxalone drug interactions.

What are the common drug interactions of Ozempic and Metaxalone, by gender? *:

female:

Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)
Gait disturbance
Hypersomnia (excessive daytime sleepiness (eds))
Limb injury
Pancreatitis (inflammation of pancreas)
Rash
Vomiting
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)

male:

Atrioventricular block complete (heart block complete)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypertension (high blood pressure)
Neuropathy peripheral (surface nerve damage)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)

What are the common drug interactions of Ozempic and Metaxalone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)

30-39:

Eyelid disorder
Hallucination (an experience involving the perception of something not present)
Headache (pain in head)
Myalgia (muscle pain)
Night sweats (sweating in night)
Panic attack
Sleep paralysis (waking up and unable to move or speak)
Vertigo

40-49:

n/a

50-59:

Neuropathy peripheral (surface nerve damage)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Pancreatitis (inflammation of pancreas)
Atrioventricular block complete (heart block complete)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypertension (high blood pressure)

60+:

Fungal skin infection
Hypersensitivity
Infection
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 23.08%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 23.08%
Nausea And Vomiting: 2 people, 15.38%
Hypersensitivity: 2 people, 15.38%
Endometrial Cancer: 2 people, 15.38%
Drowsiness: 2 people, 15.38%
Type 2 Diabetes: 1 person, 7.69%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.69%
Diabetes: 1 person, 7.69%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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