Ozempic and Prevacid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Prevacid (lansoprazole). Common drug interactions include hepatic enzyme increased among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Prevacid. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,762 Ozempic users. Check the latest studies of Ozempic.

What is Prevacid?

Prevacid has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 130,714 Prevacid users. Check the latest studies of Prevacid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

57 people who take Ozempic and Prevacid together, and have interactions are studied.

What are the common drug interactions of Ozempic and Prevacid, by gender? *:

female:

Hepatic enzyme increased
Inflammation
Infusion related reaction
Infusion site haemorrhage (bleeding from infusion site)
Infusion site pruritus (severe itching at infusion site)
Infusion site rash
Nephrolithiasis (calculi in the kidneys)
Pain in extremity
Staphylococcal infection (an infection with staphylococcus bacteria)
Tooth infection

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Palpitations (feelings or sensations that your heart is pounding or racing)
Arthralgia (joint pain)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cough
Gout (uric acid crystals building up in the body)
Hepatic steatosis (fatty liver disease)

What are the common drug interactions of Ozempic and Prevacid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Renal failure (kidney dysfunction)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)

40-49:

Blood glucose decreased
Blood pressure increased
Weight increased
Chest discomfort
Chronic kidney disease
Nephrolithiasis (calculi in the kidneys)
Pain
Accident
Cellulitis (infection under the skin)
Concussion (short loss of normal brain function in response to a head injury)

50-59:

Infusion site rash
Injection site discharge
Pain
Peripheral swelling
Pneumonia fungal
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Renal injury (kidney injury)
Rib fracture
Seasonal allergy (allergic condition due to certain season)
Sinusitis (inflammation of sinus)

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Hypertensive nephropathy (hypertensive renal disease)
Microalbuminuria (albumin into the urine)
Nephropathy (damage to or disease of a kidney)
Nocturia (the need to get up in the night to urinate)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Proteinuria (presence of protein in the urine)
Abdominal pain
Decreased appetite

What are the existing conditions these people have? *

High Blood Cholesterol: 13 people, 22.81%
Pain: 12 people, 21.05%
Diabetes: 11 people, 19.30%
High Blood Pressure: 11 people, 19.30%
Type 2 Diabetes: 10 people, 17.54%
Asthma: 8 people, 14.04%
Stress And Anxiety: 7 people, 12.28%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 10.53%
Bipolar Disorder (mood disorder): 5 people, 8.77%
Depression: 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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