Casodex and Periodontitis - a phase IV clinical study of FDA data

Summary:

Periodontitis is reported as a side effect among people who take Casodex (bicalutamide), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Periodontitis when taking Casodex. It is created by eHealthMe based on reports of 10,594 people who have side effects when taking Casodex from the FDA, and is updated regularly.

What is Casodex?

Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.

What is Periodontitis?

Periodontitis (inflammation of the tissue around the teeth) is found to be associated with 640 drugs and 709 conditions by eHealthMe. Check the latest studies of Periodontitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

10,594 people reported to have side effects when taking Casodex.
Among them, 92 people (0.87%) have Periodontitis.

Among these 92 people:

How long have people been on Casodex when they have Periodontitis? *

What is the gender of people who have Periodontitis when taking Casodex? *

female: 4.35 %
male: 95.65 %

What is the age of people who have Periodontitis when taking Casodex? *

What are other drugs people take besides Casodex? *

What are other side effects people have besides Periodontitis? *

Bone Disorder: 74 people, 80.43%
Pain: 68 people, 73.91%
Osteomyelitis (infection of bone): 67 people, 72.83%
Stress And Anxiety: 62 people, 67.39%
Pain In Jaw: 60 people, 65.22%
Osteonecrosis Of Jaw (death of bone of jaw): 60 people, 65.22%
Swelling: 55 people, 59.78%
Dyspnea (difficult or laboured breathing): 53 people, 57.61%
Anaemia (lack of blood): 51 people, 55.43%
Bone Density Decreased: 49 people, 53.26%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 44 people, 47.83%
Prostate Cancer Metastatic: 18 people, 19.57%
Pain: 11 people, 11.96%
Sleep Disorder: 10 people, 10.87%
Neoplasm Malignant (cancer tumour): 10 people, 10.87%
Bone Pain: 10 people, 10.87%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 10 people, 10.87%
Osteoporosis (bones weak and more likely to break): 5 people, 5.43%
Chest Pain: 5 people, 5.43%
Type 2 Diabetes: 4 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Casodex and have Periodontitis?

- Check whether Periodontitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Casodex:

Casodex (10,725 reports)

Periodontitis treatments and more:

Periodontitis (4,596 reports)

Browse all side effects of Casodex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Periodontitis:

Periodontitis (640 drugs)

Browse all the conditions that are associated with Periodontitis:

Periodontitis (709 conditions)

Related publications that referenced our studies

Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on bicalutamide (the active ingredients of Casodex) and Casodex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.