Ozempic and Revatio drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ozempic (semaglutide) and Revatio (sildenafil citrate). Common drug interactions include fatigue among females and epistaxis among males.
The phase IV clinical study analyzes what interactions people have when they take Ozempic and Revatio. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Ozempic?
Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.
What is Revatio?
Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.
19 people who take Ozempic and Revatio together, and have interactions are studied.

What are the common drug interactions of Ozempic and Revatio, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Dyspnoea (difficult or laboured respiration)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Hospitalisation
- Asthenia (weakness)
- Influenza
- Muscle spasms (muscle contraction)
- Nasopharyngitis (inflammation of the nasopharynx)
- Chills (felling of cold)
male:
- Epistaxis (bleed from the nose)
- Pneumonia
- Hypercholesterolaemia (high levels of cholesterol in the blood)
- Lymphoedema (localized fluid retention and tissue swelling)
- Memory impairment
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
- Pain
- Postoperative thoracic procedure complication
What are the common drug interactions of Ozempic and Revatio, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Nasopharyngitis (inflammation of the nasopharynx)
- Chills (felling of cold)
- Fatigue (feeling of tiredness)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Depression
- Device dislocation
- Device related infection
- Dyspnoea (difficult or laboured respiration)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Gait disturbance
60+:
- Epistaxis (bleed from the nose)
- Pneumonia
- Weight decreased
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Arthralgia (joint pain)
- Blood pressure increased
- Hospitalisation
- Infection
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 63.16%
- Diabetes: 2 people, 10.53%
- Type 2 Diabetes: 1 person, 5.26%
- Indigestion: 1 person, 5.26%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.26%
- Erection Problems: 1 person, 5.26%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
- High Blood Cholesterol: 1 person, 5.26%
- Hypersensitivity: 1 person, 5.26%
- Lymphoedema (localized fluid retention and tissue swelling): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Ozempic and Revatio?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ozempic and Revatio:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ozempic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Revatio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ozempic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revatio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on semaglutide and sildenafil citrate (the active ingredients of Ozempic and Revatio, respectively), and Ozempic and Revatio (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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