Pantoprazole and Kemadrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pantoprazole (pantoprazole sodium) and Kemadrin (procyclidine hydrochloride). Common drug interactions include confusional state among females and bipolar disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Pantoprazole and Kemadrin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.

What is Kemadrin?

Kemadrin has active ingredients of procyclidine hydrochloride. eHealthMe is studying from 503 Kemadrin users. Check the latest studies of Kemadrin.



On Jul, 07, 2026

16 people who take Pantoprazole and Kemadrin together, and have interactions are studied.

Pantoprazole and Kemadrin drug interactions.

What are the common drug interactions of Pantoprazole and Kemadrin, by gender? *:

female:

  1. Confusional state
  2. Hyperthermia (body temperature greatly above normal)
  3. Blood creatinine decreased
  4. Blood magnesium decreased
  5. Body temperature fluctuation
  6. Burning sensation
  7. Cold sweat
  8. Genital discomfort
  9. Hypervigilance
  10. Hypoacusis (loss of hearing)

male:

  1. Bipolar disorder (mood disorder)
  2. Aggression
  3. Abdominal discomfort
  4. Abdominal distension
  5. Abdominal pain
  6. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  7. Anxiety
  8. Balance disorder
  9. Blood pressure decreased
  10. Blood pressure increased

What are the common drug interactions of Pantoprazole and Kemadrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anxiety
  2. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  3. Hyperhidrosis (abnormally increased sweating)

30-39:

  1. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  2. Balance disorder
  3. Blood pressure decreased
  4. Overdose
  5. Vertigo

40-49:

  1. Confusional state
  2. Hyperthermia (body temperature greatly above normal)

50-59:

  1. Bipolar disorder (mood disorder)
  2. Aggression
  3. Cardiac disorder
  4. Confusional state
  5. Abnormal behaviour
  6. Headache (pain in head)
  7. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  8. Suicidal ideation
  9. Overdose
  10. Delusional disorder, unspecified type

60+:

  1. Abdominal discomfort
  2. Abdominal distension
  3. Hypoacusis (loss of hearing)
  4. Skin lesion
  5. Abdominal pain
  6. Body temperature fluctuation
  7. Burning sensation
  8. Cold sweat
  9. Decreased appetite
  10. Faecaloma (hard mass of fecal matter)

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 12.50%
  2. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 12.50%
  3. Tooth Abscess (pus formation in tooth): 1 person, 6.25%
  4. Parkinson's Disease: 1 person, 6.25%
  5. Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 1 person, 6.25%
  6. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 6.25%
  7. Asthma: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Pantoprazole and Kemadrin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pantoprazole and Kemadrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kemadrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pantoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kemadrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium and procyclidine hydrochloride (the active ingredients of Pantoprazole and Kemadrin, respectively), and Pantoprazole and Kemadrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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