Pantoprazole and Olysio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pantoprazole (pantoprazole sodium) and Olysio (simeprevir). Common drug interactions include nausea among females and hepatitis c among males.

The phase IV clinical study analyzes what interactions people have when they take Pantoprazole and Olysio. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,170 Pantoprazole users. Check the latest studies of Pantoprazole.

What is Olysio?

Olysio has active ingredients of simeprevir. eHealthMe is studying from 3,076 Olysio users. Check the latest studies of Olysio.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

33 people who take Pantoprazole and Olysio together, and have interactions are studied.

Pantoprazole and Olysio drug interactions.

What are the common drug interactions of Pantoprazole and Olysio, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Photosensitivity reaction
Abasia (inability to walk)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chills (felling of cold)
Coma (state of unconsciousness lasting more than six hours)
Death
Epistaxis (bleed from the nose)
Erythema (redness of the skin)
Eye haemorrhage (bleeding in the eye)

male:

Hepatitis c
Asthenia (weakness)
Back pain
Balance disorder
Coagulopathy (blood's ability to clot is impaired)
Decreased activity
Dysstasia (difficulty in standing)
Emotional distress
Fall
Gait disturbance

What are the common drug interactions of Pantoprazole and Olysio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Septic shock (shock due to blood infection)
Aggression
Agitation (state of anxiety or nervous excitement)
Constipation
Erythema (redness of the skin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Insomnia (sleeplessness)
Irritability
Lip swelling
Nausea (feeling of having an urge to vomit)

50-59:

Dyspnoea (difficult or laboured respiration)
Hepatitis c
Asthenia (weakness)
Balance disorder
Coagulopathy (blood's ability to clot is impaired)
Decreased appetite
Dizziness
Fall
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatocellular carcinoma (liver cancer)

60+:

Hepatitis c
Fatigue (feeling of tiredness)
Gait disturbance
Immobile (not moving)
Impaired work ability
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Nausea (feeling of having an urge to vomit)
Osteoporosis (bones weak and more likely to break)
Pain
Pain in extremity

What are the existing conditions these people have? *

Hepatitis C: 17 people, 51.52%
Depression: 6 people, 18.18%
Stress And Anxiety: 2 people, 6.06%
Portal Hypertension (increase in the blood pressure within a system of veins called the portal venous system): 2 people, 6.06%
Hypersensitivity: 2 people, 6.06%
Hiv Infection: 2 people, 6.06%
Heart Disease: 2 people, 6.06%
Diabetes: 2 people, 6.06%
Asthma: 2 people, 6.06%
Ascites (accumulation of fluid in the abdominal cavity): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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