Paracetamol and Marinol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol (acetaminophen) and Marinol (dronabinol). Common drug interactions include dyspnoea among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Marinol. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Marinol?

Marinol has active ingredients of dronabinol. It is often used in pain. eHealthMe is studying from 4,963 Marinol users. Check the latest studies of Marinol.



On Jul, 09, 2026

11 people who take Paracetamol and Marinol together, and have interactions are studied.

Paracetamol and Marinol drug interactions.

What are the common drug interactions of Paracetamol and Marinol, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Abdominal pain
  4. Arthralgia (joint pain)
  5. Constipation
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Alanine aminotransferase increased
  8. Aspartate aminotransferase increased
  9. Blood alkaline phosphatase increased
  10. Decreased appetite

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Depression
  3. Death
  4. Terminal state (the transitional states between life and biological death)
  5. Emotional distress
  6. Lethargy (tiredness)
  7. Quality of life decreased
  8. Renal failure (kidney dysfunction)
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

What are the common drug interactions of Paracetamol and Marinol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Depression
  3. Emotional distress
  4. Lethargy (tiredness)
  5. Quality of life decreased
  6. Renal failure (kidney dysfunction)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

30-39:

n/a

40-49:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Abdominal pain
  3. Anaemia (lack of blood)
  4. Arrhythmia (irregular heartbeat)
  5. Arthralgia (joint pain)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Chest pain
  8. Constipation
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Decreased activity

50-59:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Aspartate aminotransferase increased
  4. Blood alkaline phosphatase increased
  5. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  6. Vomiting

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Alanine aminotransferase increased
  3. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  4. Decreased appetite
  5. Discomfort
  6. Dry mouth
  7. Dry throat
  8. Gastritis (inflammation of stomach)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

  1. Colon Cancer: 2 people, 18.18%
  2. Stress And Anxiety: 2 people, 18.18%
  3. Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 9.09%
  4. High Blood Cholesterol: 1 person, 9.09%
  5. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 9.09%
  6. Adverse Event: 1 person, 9.09%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 9.09%
  8. Bacterial Infection: 1 person, 9.09%
  9. Bone Disorder: 1 person, 9.09%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and Marinol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paracetamol and Marinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Marinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Marinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and dronabinol (the active ingredients of Paracetamol and Marinol, respectively), and Paracetamol and Marinol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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