Zoledronic and Methylphenidate hydrochloride drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zoledronic (zoledronic acid) and Methylphenidate hydrochloride (methylphenidate hydrochloride). Common drug interactions include diarrhoea among females and basal cell carcinoma among males.
The phase IV clinical study analyzes what interactions people have when they take Zoledronic and Methylphenidate hydrochloride. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Zoledronic?
Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.
What is Methylphenidate hydrochloride?
Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,822 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.
13 people who take Zoledronic and Methylphenidate hydrochloride together, and have interactions are studied.

What are the common drug interactions of Zoledronic and Methylphenidate Hydrochloride, by gender? *:
female:
- Diarrhoea
- Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
- Transaminases increased
- Aspartate aminotransferase increased
male:
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
- Skin cancer
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Febrile neutropenia (fever with reduced white blood cells)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Pneumonia
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
What are the common drug interactions of Zoledronic and Methylphenidate Hydrochloride, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diarrhoea
- Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
- Transaminases increased
- Aspartate aminotransferase increased
50-59:
n/a
60+:
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
- Skin cancer
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Febrile neutropenia (fever with reduced white blood cells)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Pneumonia
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 11 people, 84.62%
- Depression: 10 people, 76.92%
- Neuropathy Peripheral (surface nerve damage): 10 people, 76.92%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 76.92%
- Nausea (feeling of having an urge to vomit): 10 people, 76.92%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 69.23%
- Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 69.23%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 9 people, 69.23%
- Rickets (softening of bones): 9 people, 69.23%
- Dementia (madness): 9 people, 69.23%
* Approximation only. Some reports may have incomplete information.
Do you take Zoledronic and Methylphenidate hydrochloride?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zoledronic (29,812 reports)
- Methylphenidate hydrochloride (6,822 reports)
Browse all drug interactions of Zoledronic and Methylphenidate hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zoledronic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methylphenidate hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoledronic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methylphenidate hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid and methylphenidate hydrochloride (the active ingredients of Zoledronic and Methylphenidate hydrochloride, respectively), and Zoledronic and Methylphenidate hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Drug interactions of Emla and Adriamycin Pfs - 32 seconds ago
- Could Clonidine cause Psoriatic Arthropathy Aggravated? - 37 seconds ago
- Drug interactions of Reglan and Vimpat - 43 seconds ago
- Could Dutasteride cause Liver Function Test Abnormal? - 55 seconds ago
- Drug interactions of Zestoretic and Isosorbide Mononitrate - 59 seconds ago
- Could Cimzia cause Blindness? - a minute ago
- Drug interactions of Zestoretic and Nuvigil - a minute ago
- Drug interactions of Desogestrel And Ethinyl Estradiol and Morphine Sulfate - a minute ago
- Drug interactions of Anastrozole and Tenormin - a minute ago
- Drug interactions of Diprivan and Cefazolin Sodium - a minute ago