Pataday and Hctz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pataday (olopatadine hydrochloride) and Hctz (hydrochlorothiazide). Common drug interactions include lip swelling among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Pataday and Hctz. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Pataday?

Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

On Jul, 13, 2026

40 people who take Pataday and Hctz together, and have interactions are studied.

What are the common drug interactions of Pataday and Hctz, by gender? *:

female:

Lip swelling
Liver disorder (liver diseases)
Lymphocytic infiltration (lymphocyte deposition)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Memory impairment
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Non-hodgkin's lymphoma stage iii (malignant (cancer) cells form in the lymph system- stage iii)
Chronic kidney disease
Hypoaesthesia (reduced sense of touch or sensation)

male:

Asthma
Cough
Abdominal discomfort
Decreased appetite
Disease progression
Drug ineffective
Hepatic enzyme increased
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Weight decreased

What are the common drug interactions of Pataday and Hctz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alanine aminotransferase increased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood lactate dehydrogenase increased
Blood pressure decreased
Brain injury
C-reactive protein increased
Cerebral haemorrhage (bleeding within the brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

30-39:

n/a

40-49:

Thermal burn (burn by heat)
Influenza like illness
Lip swelling
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Road traffic accident
Scab (a hard coating on the skin formed during the wound healing)

50-59:

Chronic kidney disease
Abdominal pain upper
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypoaesthesia (reduced sense of touch or sensation)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Psoriasis (immune-mediated disease that affects the skin)
Weight increased
Knee arthroplasty
Upper limb fracture

60+:

Asthma
Cough
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Fall
Head injury
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Injection site bruising

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 32.50%
Pain: 7 people, 17.50%
High Blood Cholesterol: 7 people, 17.50%
Stress And Anxiety: 5 people, 12.50%
Thyroid Diseases: 4 people, 10.00%
Menopause (end of monthly cycles in women): 4 people, 10.00%
Asthma: 4 people, 10.00%
Blood Pressure Abnormal: 4 people, 10.00%
Cardiac Disorder: 4 people, 10.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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