Paxil and Alimta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil (paroxetine hydrochloride) and Alimta (pemetrexed disodium). Common drug interactions include white blood cell count decreased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil and Alimta. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Alimta?

Alimta has active ingredients of pemetrexed disodium. eHealthMe is studying from 7,702 Alimta users. Check the latest studies of Alimta.

On Aug, 07, 2026

22 people who take Paxil and Alimta together, and have interactions are studied.

What are the common drug interactions of Paxil and Alimta, by gender? *:

female:

White blood cell count decreased
Pneumonia
Malignant neoplasm progression (cancer tumour came back)
Pyrexia (fever)
Alanine aminotransferase increased
Anaemia (lack of blood)
Aspartate aminotransferase increased
Asthenia (weakness)
Blood alkaline phosphatase increased
Blood glucose increased

male:

Anaemia (lack of blood)
Asthenia (weakness)
Enteritis (inflammation of the small intestine)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Genital labial adhesions (inner lips of the external female genitals (labia minora) have stuck together)
Hypotension (abnormally low blood pressure)
Hypovolaemia (a decreased volume of circulating blood in the body)
Ingrowing nail
Injection site extravasation (flow of (blood or lymph) from injection site)
Interstitial lung disease

What are the common drug interactions of Paxil and Alimta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)

50-59:

Pneumonia
Pyrexia (fever)
Neutropenia (an abnormally low number of neutrophils)
Abdominal pain
Aggression
Chest pain
Device related infection
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dyspnoea (difficult or laboured respiration)

60+:

Anaemia (lack of blood)
Interstitial lung disease
Nausea (feeling of having an urge to vomit)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Vomiting
Alanine aminotransferase increased
Aortic disorder
Aspartate aminotransferase increased
Blood alkaline phosphatase increased

What are the existing conditions these people have? *

Lung Cancer Metastatic (lung cancer spreads to other parts): 8 people, 36.36%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 27.27%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 3 people, 13.64%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 9.09%
Pain: 2 people, 9.09%
Non-Small Cell Lung Cancer Stage Iiib: 2 people, 9.09%
Diabetes: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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