Pemetrexed and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pemetrexed (pemetrexed) and Wellbutrin (bupropion hydrochloride). Common drug interactions include cardiac arrest among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Pemetrexed and Wellbutrin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,107 Wellbutrin users. Check the latest studies of Wellbutrin.

On Jul, 11, 2026

37 people who take Pemetrexed and Wellbutrin together, and have interactions are studied.

Pemetrexed and Wellbutrin drug interactions.

What are the common drug interactions of Pemetrexed and Wellbutrin, by gender? *:

female:

Cardiac arrest
Dyspnoea (difficult or laboured respiration)
Dysphonia (speech disorder attributable to a disorder of phonation)
Lip swelling
Local swelling (swelling at the site of some application of substance or injury)
Pulmonary embolism (blockage of the main artery of the lung)
Road traffic accident
Swollen tongue (swelling of tongue)
Abdominal pain
Asthenia (weakness)

male:

Pneumonia
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary tract infection
Small intestinal obstruction (blockage in small intestine)

What are the common drug interactions of Pemetrexed and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Blood iron decreased
Bone pain
Dysphagia (a condition in which swallowing is difficult or painful)
Fungal infection
Infection
Neoplasm progression (growth of tumour)
Non-small cell lung cancer metastatic (type of epithelial lung cancer spreads to other parts)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
Oesophageal fistula (a birth defect, with the trachea connected to the oesophagus)

50-59:

Dehydration (dryness resulting from the removal of water)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Asthenia (weakness)
Cholecystitis chronic (long lasting infection of gallbladder)
Dyspnoea (difficult or laboured respiration)
Hypokalaemia (low potassium)
Injury
Pain
Quality of life decreased

60+:

Pneumonia
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Fall
Hyperbilirubinaemia (excess of bilirubin in the blood)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary tract infection

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 23 people, 62.16%
Pain: 19 people, 51.35%
Nausea (feeling of having an urge to vomit): 14 people, 37.84%
High Blood Pressure: 10 people, 27.03%
Quit Smoking: 8 people, 21.62%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 8 people, 21.62%
Non-Small Cell Lung Cancer Stage Iv: 6 people, 16.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.51%
Asthma: 5 people, 13.51%
Stress And Anxiety: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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