Penlac and Amoxicillin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Penlac (ciclopirox) and Amoxicillin (amoxicillin). Common drug interactions include impaired healing among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Penlac and Amoxicillin. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Penlac?
Penlac has active ingredients of ciclopirox. eHealthMe is studying from 492 Penlac users. Check the latest studies of Penlac.
What is Amoxicillin?
Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.
28 people who take Penlac and Amoxicillin together, and have interactions are studied.

What are the common drug interactions of Penlac and Amoxicillin, by gender? *:
female:
- Impaired healing
- Loose tooth
- Osteonecrosis of jaw (death of bone of jaw)
- Osteoporosis (bones weak and more likely to break)
- Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
- Photopsia (presence of perceived flashes of light)
- Posterior capsule opacification
- Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
- Tooth disorder (tooth disease)
- Visual acuity reduced (reduced clearness of vision)
male:
- Chronic kidney disease
- Decreased appetite
- Bone density increased
- Bone disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Calcinosis (calcium deposits in any soft tissue)
- Cardiac arrest
- Carotid artery stenosis (narrowing of carotid artery)
- Cellulitis (infection under the skin)
- Cerebral atrophy (decrement in size of brain)
What are the common drug interactions of Penlac and Amoxicillin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Actinic keratosis (skin disease due to sun exposure)
- Adenomyosis (presence of ectopic glandular tissue found in muscle)
- Anaemia (lack of blood)
- Anxiety
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Balance disorder
- Bone density increased
- Bone disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Calcinosis (calcium deposits in any soft tissue)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
- Constipation
- Cough
- Deafness
- Deformity (disfigurement)
- Depression
- Dysarthria (speech disorder)
- Dysgraphia (impaired ability to learn to write)
- Dyspepsia (indigestion)
- Dystonia (abnormal muscle tone)
60+:
- Pain
- Anxiety
- Osteoporosis (bones weak and more likely to break)
- Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
- Photopsia (presence of perceived flashes of light)
- Posterior capsule opacification
- Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
- Tooth disorder (tooth disease)
- Visual acuity reduced (reduced clearness of vision)
- Visual impairment
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.29%
- Inflammation: 3 people, 10.71%
- Cardiac Disorder: 3 people, 10.71%
- Vitamin E Deficiency: 2 people, 7.14%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.14%
- Hypertensive Heart Disease: 2 people, 7.14%
- High Blood Cholesterol: 2 people, 7.14%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 7.14%
- Diabetes: 2 people, 7.14%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Penlac and Amoxicillin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Penlac (492 reports)
- Amoxicillin (99,235 reports)
Browse all drug interactions of Penlac and Amoxicillin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Penlac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Amoxicillin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Penlac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amoxicillin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ciclopirox and amoxicillin (the active ingredients of Penlac and Amoxicillin, respectively), and Penlac and Amoxicillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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