Pepcid ac and Pregabalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid ac (famotidine) and Pregabalin (pregabalin). Common drug interactions include fall among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid ac and Pregabalin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,071 Pregabalin users. Check the latest studies of Pregabalin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

26 people who take Pepcid ac and Pregabalin together, and have interactions are studied.

Pepcid ac and Pregabalin drug interactions.

What are the common drug interactions of Pepcid Ac and Pregabalin, by gender? *:

female:

Fall
Malaise (a feeling of general discomfort or uneasiness)
Dizziness
Infection
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Injection site pruritus (severe itching at injection site)
Nasopharyngitis (inflammation of the nasopharynx)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Tooth infection

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hepatic steatosis (fatty liver disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Neoplasm (tumour)
Nephrogenic anaemia (anaemia due to kidney disease)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)

What are the common drug interactions of Pepcid Ac and Pregabalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Affect lability (emotional incontinence)
Delirium (wild excitement)
Drug eruption (adverse drug reaction of the skin)
Hallucination (an experience involving the perception of something not present)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Psychotic disorder
Restlessness (not able to rest)

40-49:

n/a

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Renal impairment (severely reduced kidney function)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal injury (kidney injury)

60+:

Blood immunoglobulin g decreased
Dizziness
Nasopharyngitis (inflammation of the nasopharynx)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Tooth infection
Arthropathy
Blood calcium increased
Chronic kidney disease
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Primary Immunodeficiency Syndrome: 4 people, 15.38%
Immunodeficiency Common Variable: 4 people, 15.38%
High Blood Pressure: 4 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 11.54%
Pain: 3 people, 11.54%
Hypersensitivity: 3 people, 11.54%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 11.54%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 11.54%
Urinary Tract Infection: 2 people, 7.69%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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