Pepcid and Valacyclovir hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Valacyclovir hydrochloride (valacyclovir hydrochloride). Common drug interactions include brain injury among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

On Jul, 13, 2026

47 people who take Pepcid and Valacyclovir hydrochloride together, and have interactions are studied.

Pepcid and Valacyclovir hydrochloride drug interactions.

What are the common drug interactions of Pepcid and Valacyclovir Hydrochloride, by gender? *:

female:

Brain injury
Carotid artery stenosis (narrowing of carotid artery)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

male:

Dyspnoea (difficult or laboured respiration)
Cough
Cyst (a closed sac)
Dermal cyst
Diarrhoea
Drug resistance (reduction in effectiveness of a drug)
Emotional distress
Fatigue (feeling of tiredness)
Gastrointestinal infection (infection of stomach and intestine)
Headache (pain in head)

What are the common drug interactions of Pepcid and Valacyclovir Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Rectal haemorrhage (bleeding from anus)

30-39:

Fatigue (feeling of tiredness)
Abdominal distension
Acne (skin problems that cause pimples)
Diarrhoea
Injection site bruising
Peripheral swelling
Weight increased
Cough
Pain
Upper-airway cough syndrome

40-49:

Hunger
Injection site irritation
Insomnia (sleeplessness)
Limb injury
Muscle rupture (tear in muscle)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Nocturia (the need to get up in the night to urinate)
Oral herpes (viral infection of mouth)

50-59:

Cough
Dyspnoea (difficult or laboured respiration)
Renal impairment (severely reduced kidney function)

60+:

Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hepatic enzyme increased
Hyperglycaemia (high blood sugar)
Hypokalaemia (low potassium)
Intervertebral disc degeneration (spinal disc degeneration)
Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
Oedema (fluid collection in tissue)
Pain
Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 21.28%
Pain: 6 people, 12.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 10.64%
Hypersensitivity: 4 people, 8.51%
Stress And Anxiety: 3 people, 6.38%
Sleep Disorder: 3 people, 6.38%
Muscle Spasms (muscle contraction): 3 people, 6.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.38%
High Blood Pressure: 3 people, 6.38%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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