Peppermint and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peppermint (peppermint) and Wellbutrin (bupropion hydrochloride). Common drug interactions include anhedonia among females and burning sensation among males.

The phase IV clinical study analyzes what interactions people have when they take Peppermint and Wellbutrin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Peppermint?

Peppermint has active ingredients of peppermint. eHealthMe is studying from 1,327 Peppermint users. Check the latest studies of Peppermint.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,107 Wellbutrin users. Check the latest studies of Wellbutrin.



On Jul, 18, 2026

11 people who take Peppermint and Wellbutrin together, and have interactions are studied.

Peppermint and Wellbutrin drug interactions.

What are the common drug interactions of Peppermint and Wellbutrin, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Asthenia (weakness)
  3. Body temperature increased
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Burning sensation
  6. Chest discomfort
  7. Cough
  8. Cystitis (inflammation of the wall of the bladder)
  9. Dermatitis allergic (inflammation of the skin due allergic reaction)
  10. Diarrhoea

male:

  1. Burning sensation
  2. Gait disturbance
  3. Pain in extremity

What are the common drug interactions of Peppermint and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal pain
  2. Burning sensation
  3. Diarrhoea
  4. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  5. Muscle twitching
  6. Nightmare (unpleasant dream)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Skin tightness

30-39:

  1. Weight increased
  2. Gastric bypass

40-49:

  1. Body temperature increased
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Chest discomfort
  4. Cough
  5. Cystitis (inflammation of the wall of the bladder)
  6. Fatigue (feeling of tiredness)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Pyrexia (fever)
  9. Upper respiratory tract infection

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 45.45%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 18.18%
  3. Asthma: 2 people, 18.18%
  4. Stress And Anxiety: 1 person, 9.09%
  5. Seasonal Allergy (allergic condition due to certain season): 1 person, 9.09%
  6. Rickets (softening of bones): 1 person, 9.09%
  7. Pain: 1 person, 9.09%
  8. Nausea (feeling of having an urge to vomit): 1 person, 9.09%
  9. Iron Deficiency Anaemia: 1 person, 9.09%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Peppermint and Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peppermint:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peppermint and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Wellbutrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on peppermint and bupropion hydrochloride (the active ingredients of Peppermint and Wellbutrin, respectively), and Peppermint and Wellbutrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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