Perforomist and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Perforomist (formoterol fumarate) and Simvastatin (simvastatin). Common drug interactions include international normalised ratio increased among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Perforomist and Simvastatin. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Perforomist?

Perforomist has active ingredients of formoterol fumarate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 1,431 Perforomist users. Check the latest studies of Perforomist.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

On Jul, 16, 2026

75 people who take Perforomist and Simvastatin together, and have interactions are studied.

Perforomist and Simvastatin drug interactions.

What are the common drug interactions of Perforomist and Simvastatin, by gender? *:

female:

International normalised ratio increased
Mouth haemorrhage (bleeding from mouth)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neuropathy peripheral (surface nerve damage)
Productive cough
Pulmonary oedema (fluid accumulation in the lungs)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

Dyspnoea (difficult or laboured respiration)
Cardiac disorder
Death
Dehydration (dryness resulting from the removal of water)
Dementia (madness)
Drug effect decreased
Drug hypersensitivity
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
General physical health deterioration (weak health status)

What are the common drug interactions of Perforomist and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Abdominal pain upper
Drug effect decreased
Drug ineffective
Influenza
Insomnia (sleeplessness)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

Drug ineffective
Renal failure (kidney dysfunction)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Anticonvulsant drug level increased
Cardiac disorder
Gait disturbance
Lung disorder (lung disease)
Anticonvulsant drug level decreased
Balance disorder
Chronic kidney disease

60+:

Pain in extremity
Dyspnoea (difficult or laboured respiration)
Respiratory distress (difficulty in breathing)
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Haemorrhage (bleeding)
Aphasia (damage to the parts of the brain that control language)
Malaise (a feeling of general discomfort or uneasiness)
Cardiac failure congestive
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 15 people, 20.00%
Neuralgia (pain in one or more nerves): 13 people, 17.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 14.67%
Weight Increased: 9 people, 12.00%
Gout (uric acid crystals building up in the body): 9 people, 12.00%
High Blood Pressure: 9 people, 12.00%
Dyspnea (difficult or laboured breathing): 8 people, 10.67%
Immunodeficiency Common Variable: 7 people, 9.33%
Stress And Anxiety: 7 people, 9.33%
Pain: 7 people, 9.33%

* Approximation only. Some reports may have incomplete information.

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