Periactin and Lansoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Periactin (cyproheptadine hydrochloride) and Lansoprazole (lansoprazole). Common drug interactions include abdominal pain among females and urinary retention among males.

The phase IV clinical study analyzes what interactions people have when they take Periactin and Lansoprazole. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Periactin?

Periactin has active ingredients of cyproheptadine hydrochloride. It is often used in migraine. eHealthMe is studying from 2,214 Periactin users. Check the latest studies of Periactin.

What is Lansoprazole?

Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.



On Jul, 27, 2026

23 people who take Periactin and Lansoprazole together, and have interactions are studied.

Periactin and Lansoprazole drug interactions.

What are the common drug interactions of Periactin and Lansoprazole, by gender? *:

female:

  1. Abdominal pain
  2. Appendicitis (inflammation of the appendix)
  3. Constipation
  4. Depression
  5. Faecal volume increased
  6. Intestinal pseudo-obstruction (syndrome caused by severe impairment in the ability of the intestines to push food through)
  7. Suicide attempt
  8. Balance disorder
  9. Blood magnesium decreased
  10. Blood potassium decreased

male:

  1. Urinary retention (the inability to completely or partially empty the bladder)
  2. Urinary tract infection
  3. Pleural effusion (water on the lungs)
  4. Vertigo
  5. Abdominal pain
  6. Acute respiratory distress syndrome
  7. Agitation (state of anxiety or nervous excitement)
  8. Anaemia (lack of blood)
  9. Asplenia (absence of normal spleen function and is associated with some serious infection risks)
  10. Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Periactin and Lansoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Diarrhoea
  2. Abdominal pain
  3. Acute respiratory distress syndrome
  4. Agitation (state of anxiety or nervous excitement)
  5. Anaemia (lack of blood)
  6. Asplenia (absence of normal spleen function and is associated with some serious infection risks)
  7. Atelectasis (partial or complete collapse of the lung)
  8. Bladder hypertrophy (bladder overgrowth- increase in cell size)
  9. Bone marrow disorder
  10. Cardiac arrest

10-19:

  1. Abdominal pain
  2. Appendicitis (inflammation of the appendix)
  3. Constipation
  4. Depression
  5. Faecal volume increased
  6. Intestinal pseudo-obstruction (syndrome caused by severe impairment in the ability of the intestines to push food through)
  7. Suicide attempt
  8. Blood magnesium decreased
  9. Blood potassium decreased
  10. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Urinary retention (the inability to completely or partially empty the bladder)
  2. Urinary tract infection
  3. Bone marrow failure
  4. Cerebral infarction (less blood supply to brain resulting tissue damage)
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Depressed level of consciousness
  7. General physical health deterioration (weak health status)
  8. Oxygen saturation decreased
  9. Pleural effusion (water on the lungs)
  10. Pneumonia

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 6 people, 26.09%
  2. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 4 people, 17.39%
  3. Nausea And Vomiting: 3 people, 13.04%
  4. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.70%
  5. Sleep Disorder: 2 people, 8.70%
  6. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 8.70%
  7. Overgrowth Bacterial (extra growth due to bacteria): 2 people, 8.70%
  8. Itching: 2 people, 8.70%
  9. Dry Skin: 2 people, 8.70%
  10. Cystic Fibrosis (disease of the secretary glands): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Periactin and Lansoprazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Periactin and Lansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Periactin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Periactin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lansoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cyproheptadine hydrochloride and lansoprazole (the active ingredients of Periactin and Lansoprazole, respectively), and Periactin and Lansoprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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