Phenergan w/ codeine and Aspirin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phenergan w/ codeine (codeine phosphate; promethazine hydrochloride) and Aspirin (aspirin). Common drug interactions include anxiety among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Phenergan w/ codeine and Aspirin. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Phenergan w/ codeine?

Phenergan w/ codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 179 Phenergan w/ codeine users. Check the latest studies of Phenergan w/ codeine.

What is Aspirin?

Aspirin has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 632,089 Aspirin users. Check the latest studies of Aspirin.

On Aug, 01, 2026

23 people who take Phenergan w/ codeine and Aspirin together, and have interactions are studied.

Phenergan w/ codeine and Aspirin drug interactions.

What are the common drug interactions of Phenergan W/ Codeine and Aspirin, by gender? *:

female:

Anxiety
Depression
Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatomegaly (abnormal enlargement of the liver)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Iron deficiency
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)

male:

Dizziness
Haemoglobin decreased
Dysphonia (speech disorder attributable to a disorder of phonation)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Malignant neoplasm progression (cancer tumour came back)
Neuropathy peripheral (surface nerve damage)
Pallor
Skin warm
Type 2 diabetes mellitus

What are the common drug interactions of Phenergan W/ Codeine and Aspirin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Neuropathy peripheral (surface nerve damage)
Pancreatitis (inflammation of pancreas)
Type 2 diabetes mellitus

40-49:

Gastroenteritis (inflammation of stomach and intestine)

50-59:

Atelectasis (partial or complete collapse of the lung)
Back pain
Balanitis candida (inflammation of the glands penis by infection with candida albicans)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cerebellar infarction (impaired blood circulation to cerebellum)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
Cerebral artery stenosis (hardening of brain blood vessels)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

Diarrhoea
Anxiety
Dysphonia (speech disorder attributable to a disorder of phonation)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemoglobin decreased
Hepatomegaly (abnormal enlargement of the liver)
Iron deficiency
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.04%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 13.04%
Sleep Disorder: 2 people, 8.70%
Renal Cell Carcinoma (a kidney cancer): 2 people, 8.70%
Oral Herpes (viral infection of mouth): 2 people, 8.70%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 8.70%
Gait Disturbance: 2 people, 8.70%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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