Pravastatin sodium and Contrave drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pravastatin sodium (pravastatin sodium) and Contrave (bupropion hydrochloride; naltrexone hydrochloride). Common drug interactions include burn oesophageal among females and prostatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Pravastatin sodium and Contrave. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Pravastatin sodium?

Pravastatin sodium has active ingredients of pravastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 26,520 Pravastatin sodium users. Check the latest studies of Pravastatin sodium.

What is Contrave?

Contrave has active ingredients of bupropion hydrochloride; naltrexone hydrochloride. It is often used in weight loss. eHealthMe is studying from 5,553 Contrave users. Check the latest studies of Contrave.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

15 people who take Pravastatin sodium and Contrave together, and have interactions are studied.

Pravastatin sodium and Contrave drug interactions.

What are the common drug interactions of Pravastatin Sodium and Contrave, by gender? *:

female:

Burn oesophageal (burn in the oesophagus)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)
Injection site swelling
Injection site warmth
Memory impairment
Oral mucosal blistering (mouth ulcer)
Psoriasis (immune-mediated disease that affects the skin)
Sinusitis (inflammation of sinus)

male:

Prostatitis (inflammation of the prostate gland)

What are the common drug interactions of Pravastatin Sodium and Contrave, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Injection site swelling
Injection site warmth
Oral mucosal blistering (mouth ulcer)
Prostatitis (inflammation of the prostate gland)
Psoriasis (immune-mediated disease that affects the skin)
Sinusitis (inflammation of sinus)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
C-reactive protein increased
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Injection site erythema (redness at injection site)

60+:

Burn oesophageal (burn in the oesophagus)
Depression
Drug ineffective
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Wheezing (a high-pitched whistling sound made while you breath): 5 people, 33.33%
Dyspnea (difficult or laboured breathing): 5 people, 33.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 33.33%
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below): 5 people, 33.33%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 33.33%
Joint Pain: 5 people, 33.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 33.33%
Neuralgia (pain in one or more nerves): 5 people, 33.33%
Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 5 people, 33.33%
Muscle Spasms (muscle contraction): 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

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