Precose and Fosamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Precose (acarbose) and Fosamax (alendronate sodium). Common drug interactions include femur fracture among females and haematoma among males.

The phase IV clinical study analyzes what interactions people have when they take Precose and Fosamax. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Precose?

Precose has active ingredients of acarbose. eHealthMe is studying from 1,189 Precose users. Check the latest studies of Precose.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 105,452 Fosamax users. Check the latest studies of Fosamax.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

18 people who take Precose and Fosamax together, and have interactions are studied.

What are the common drug interactions of Precose and Fosamax, by gender? *:

female:

Femur fracture
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Arthralgia (joint pain)
Asthma
Bone disorder
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Mobility decreased (ability to move is reduced)

male:

Haematoma (collection of blood outside the blood vessels)
Arthralgia (joint pain)
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Mass
Mobility decreased (ability to move is reduced)
Monoparesis (one limb is very weak, but not completely paralyzed)
Muscle injury

What are the common drug interactions of Precose and Fosamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Bone disorder
Dysstasia (difficulty in standing)
Femur fracture
Fracture delayed union (delayed cure of broken bone)
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Haematoma (collection of blood outside the blood vessels)
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)

40-49:

n/a

50-59:

Femur fracture
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Arthralgia (joint pain)
Bone disorder
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Mobility decreased (ability to move is reduced)
Osteoporotic fracture (fracture due to weak bone)

60+:

Weight increased
Accident
Injection site bruising
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Pruritus generalised (generalized itching)
Syncope (loss of consciousness with an inability to maintain postural tone)
Therapeutic response unexpected
Thinking abnormal
Tooth abscess (pus formation in tooth)

What are the existing conditions these people have? *

Asthma: 4 people, 22.22%
Diabetes: 2 people, 11.11%
Type 2 Diabetes: 1 person, 5.56%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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