Prednisone and Tukysa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Tukysa (tucatinib). Common drug interactions include diarrhoea among females.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Tukysa. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Tukysa?

Tukysa has active ingredients of tucatinib. eHealthMe is studying from 3,216 Tukysa users. Check the latest studies of Tukysa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

20 people who take Prednisone and Tukysa together, and have interactions are studied.

Prednisone and Tukysa drug interactions.

What are the common drug interactions of Prednisone and Tukysa, by gender? *:

female:

Diarrhoea
Pruritus (severe itching of the skin)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dry skin
Gastrointestinal infection (infection of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypersensitivity
Memory impairment
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscle spasms (muscle contraction)

male:

n/a

What are the common drug interactions of Prednisone and Tukysa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Mean cell volume increased (more than normal average red blood cell volume)
Nodule (a growth of abnormal tissue)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral sensorimotor neuropathy (damage to one or more of your peripheral nerves)
Platelet count decreased
Rash
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Coagulation factor decreased (less clotting substance in blood)
Hepatotoxicity (chemical-driven liver damage)
Hyperbilirubinaemia (excess of bilirubin in the blood)

60+:

Pruritus (severe itching of the skin)
Death

What are the existing conditions these people have? *

Breast Cancer Female: 10 people, 50.00%
Hypersensitivity: 4 people, 20.00%
Peripheral Swelling: 3 people, 15.00%
Insomnia (sleeplessness): 3 people, 15.00%
Breast Cancer Stage Iv: 3 people, 15.00%
Breast Cancer: 2 people, 10.00%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.00%
Stress And Anxiety: 1 person, 5.00%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 5.00%
Diarrhea: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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