Premphase and Xanax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Premphase (estrogens, conjugated; medroxyprogesterone acetate) and Xanax (alprazolam). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Premphase and Xanax. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Premphase?

Premphase has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. eHealthMe is studying from 2,262 Premphase users. Check the latest studies of Premphase.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

On Jul, 09, 2026

34 people who take Premphase and Xanax together, and have interactions are studied.

What are the common drug interactions of Premphase and Xanax, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Vomiting
Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Bone disorder
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac arrest

male:

n/a

What are the common drug interactions of Premphase and Xanax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Anaphylactic reaction (serious allergic reaction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angioedema (rapid swelling of the dermis)
Arrhythmia (irregular heartbeat)
Arteritis (inflammation of the walls of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Depression
Flatulence (flatus expelled through the anus)
Abnormal dreams
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fall
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hyperhidrosis (abnormally increased sweating)
Injury

50-59:

Liver disorder (liver diseases)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Osteopenia (a condition where bone mineral density is lower than normal)
Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
Vomiting
Breast cancer
Abdominal pain
Abnormal behaviour

60+:

Fatigue (feeling of tiredness)
Abdominal pain
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac arrest
Cardiac failure chronic
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dental caries

What are the existing conditions these people have? *

Pain In Jaw: 10 people, 29.41%
Multiple Myeloma (cancer of the plasma cells): 10 people, 29.41%
Menopause (end of monthly cycles in women): 7 people, 20.59%
Depression: 6 people, 17.65%
Quit Smoking: 3 people, 8.82%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 8.82%
Pain: 2 people, 5.88%
Insomnia (sleeplessness): 2 people, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.88%
Constipation: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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