Prevpac and Vioxx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prevpac (amoxicillin; clarithromycin; lansoprazole) and Vioxx (rofecoxib). Common drug interactions include constipation among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Prevpac and Vioxx. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Prevpac?

Prevpac has active ingredients of amoxicillin; clarithromycin; lansoprazole. It is often used in helicobacter pylori. eHealthMe is studying from 758 Prevpac users. Check the latest studies of Prevpac.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 110,130 Vioxx users. Check the latest studies of Vioxx.

On Jul, 15, 2026

24 people who take Prevpac and Vioxx together, and have interactions are studied.

What are the common drug interactions of Prevpac and Vioxx, by gender? *:

female:

Constipation
Injury
Joint injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal discomfort
Abdominal haematoma (collection of blood within the abdominal wall musculature)
Anger
Anxiety

male:

Anaemia (lack of blood)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Haematuria (presence of blood in urine)
Heart rate irregular
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Renal cyst (kidney cyst)
Weight increased
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Cardiac murmur (an heart sound in valve abnormality)
Dyspnoea exertional (breathlessness or shortness of breath)

What are the common drug interactions of Prevpac and Vioxx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood pressure increased
Abdominal pain upper
Chest pain
Peptic ulcer
Abdominal pain
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arthropathy
Back injury

50-59:

Flushing (the warm, red condition of human skin)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Palpitations (feelings or sensations that your heart is pounding or racing)
Nephrolithiasis (calculi in the kidneys)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Essential hypertension (primary hypertension)
Abdominal discomfort
Anger
Anxiety
Arteriosclerosis (thickening and hardening of arteries)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Wrist fracture
Abdominal distension
Acquired cardiac septal defect (hole in the heart)
Anaemia (lack of blood)
Anxiety
Apnoea (suspension of external breathing)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthropathy

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 54.17%
High Blood Cholesterol: 10 people, 41.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.67%
Joint Pain: 3 people, 12.50%
Depression: 3 people, 12.50%
Cardiac Disorder: 3 people, 12.50%
Pain: 2 people, 8.33%
Multiple Allergies (allergy to multiple agents): 2 people, 8.33%
Monarthritis (inflammation (arthritis) of one joint at a time): 2 people, 8.33%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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