Prilosec and B6 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and B6 (pyridoxine (vitamin b6)). Common drug interactions include full blood count decreased among females and blood iron increased among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and B6. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

What is B6?

B6 has active ingredients of pyridoxine (vitamin b6). eHealthMe is studying from 1,043 B6 users. Check the latest studies of B6.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

29 people who take Prilosec and B6 together, and have interactions are studied.

What are the common drug interactions of Prilosec and B6, by gender? *:

female:

Full blood count decreased
Abasia (inability to walk)
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Central nervous system viral infection
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Fatigue (feeling of tiredness)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Pregnancy

male:

Blood iron increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Onychomadesis (a periodic idiopathic shedding of the nails)
Pain
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Pruritus (severe itching of the skin)
Rash
Serum serotonin increased

What are the common drug interactions of Prilosec and B6, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Pruritus (severe itching of the skin)

30-39:

Blood iron increased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

40-49:

n/a

50-59:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Arthralgia (joint pain)
Asthma
Bed bug infestation
Chronic kidney disease
Depressed mood
Diarrhoea
Dysarthria (speech disorder)
Fatigue (feeling of tiredness)
Gait disturbance

60+:

Full blood count decreased
Abasia (inability to walk)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood potassium increased
Chills (felling of cold)
Death
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the existing conditions these people have? *

Constipation: 5 people, 17.24%
Pain: 5 people, 17.24%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 13.79%
High Blood Cholesterol: 3 people, 10.34%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 10.34%
Hypersensitivity: 3 people, 10.34%
Multiple Myeloma (cancer of the plasma cells): 3 people, 10.34%
Visual Impairment: 2 people, 6.90%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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