Prilosec and Kesimpta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Kesimpta (ofatumumab). Common drug interactions include extraocular muscle disorder among females and influenza like illness among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Kesimpta. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Kesimpta?

Kesimpta has active ingredients of ofatumumab. eHealthMe is studying from 36,592 Kesimpta users. Check the latest studies of Kesimpta.



On Jul, 25, 2026

65 people who take Prilosec and Kesimpta together, and have interactions are studied.

Prilosec and Kesimpta drug interactions.

What are the common drug interactions of Prilosec and Kesimpta, by gender? *:

female:

  1. Extraocular muscle disorder (eye movement disorder)
  2. Gastric bypass
  3. Glaucoma (increased fluid pressure in the eye with vision loss)
  4. Grip strength decreased
  5. Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
  6. Fatigue (feeling of tiredness)
  7. Pyrexia (fever)
  8. Headache (pain in head)
  9. Pain in extremity
  10. Abdominal discomfort

male:

  1. Influenza like illness
  2. Pyrexia (fever)
  3. Blood pressure increased
  4. Chills (felling of cold)
  5. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  6. Asthenia (weakness)
  7. Swelling face
  8. Cellulitis (infection under the skin)
  9. Drug ineffective
  10. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

What are the common drug interactions of Prilosec and Kesimpta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Fatigue (feeling of tiredness)
  2. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  3. Neuralgia (pain in one or more nerves)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Vision blurred
  6. Abdominal discomfort
  7. Headache (pain in head)
  8. Herpes zoster
  9. Hyperchlorhydria (gastric acid levels are higher in stomach)
  10. Influenza like illness

40-49:

  1. Depression
  2. Drug ineffective
  3. Pyrexia (fever)
  4. Anaemia (lack of blood)
  5. Asthma
  6. Breast swelling
  7. Breast tenderness
  8. Chest pain
  9. Costochondritis (chest wall pain)
  10. Dyspepsia (indigestion)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Pyrexia (fever)
  3. Abdominal distension
  4. Fall
  5. Influenza like illness
  6. Nausea (feeling of having an urge to vomit)
  7. Wrist fracture
  8. Abdominal pain lower
  9. Balance disorder
  10. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

60+:

  1. Pyrexia (fever)
  2. Arthralgia (joint pain)
  3. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Confusional state
  6. Dehydration (dryness resulting from the removal of water)
  7. Ejection fraction decreased (systolic heart failure)
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
  10. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 59 people, 90.77%
  2. Stress And Anxiety: 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and Kesimpta?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prilosec and Kesimpta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kesimpta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kesimpta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole and ofatumumab (the active ingredients of Prilosec and Kesimpta, respectively), and Prilosec and Kesimpta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: