Centrum silver and Fludrocortisone acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Fludrocortisone acetate (fludrocortisone acetate). Common drug interactions include hallucination among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum silver and Fludrocortisone acetate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.

What is Fludrocortisone acetate?

Fludrocortisone acetate has active ingredients of fludrocortisone acetate. It is often used in hypotension. eHealthMe is studying from 2,859 Fludrocortisone acetate users. Check the latest studies of Fludrocortisone acetate.



On Jul, 25, 2026

18 people who take Centrum silver and Fludrocortisone acetate together, and have interactions are studied.

Centrum silver and Fludrocortisone acetate drug interactions.

What are the common drug interactions of Centrum Silver and Fludrocortisone Acetate, by gender? *:

female:

  1. Hallucination (an experience involving the perception of something not present)
  2. Fall
  3. Orthopnoea (shortness of breath (dyspnea) when lying down)
  4. Drug ineffective
  5. Hospitalisation
  6. Nocturnal dyspnoea (attacks of severe shortness of breath and coughing that generally occur at night)
  7. Pulmonary thrombosis (scarring in the lungs)
  8. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  9. Anxiety
  10. Asthenia (weakness)

male:

  1. Death
  2. Rash
  3. Urticaria (rash of round, red welts on the skin that itch intensely)
  4. Cardiac disorder
  5. Dizziness
  6. Hot flush (sudden feelings of heat)
  7. Loss of consciousness
  8. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Centrum Silver and Fludrocortisone Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Asthenia (weakness)
  5. Blood glucose increased
  6. Blood pressure fluctuation
  7. Cardiac disorder
  8. Cellulitis (infection under the skin)
  9. Cough
  10. Fibromyalgia (a long-term condition which causes pain all over the body)

What are the existing conditions these people have? *

  1. Delusion (a false belief or opinion): 5 people, 27.78%
  2. Parkinson's Disease: 5 people, 27.78%
  3. Hallucinations (sensations that appear real but are created by your mind): 5 people, 27.78%
  4. Multiple Myeloma (cancer of the plasma cells): 4 people, 22.22%
  5. Hyperkalemia (damage to or disease of the kidney): 2 people, 11.11%
  6. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 11.11%
  7. Fainting (loss of consciousness and postural tone): 1 person, 5.56%
  8. Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 1 person, 5.56%
  9. Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 1 person, 5.56%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Centrum silver and Fludrocortisone acetate:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fludrocortisone acetate:

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Browse all interactions between Centrum silver and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fludrocortisone acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and fludrocortisone acetate (the active ingredients of Centrum silver and Fludrocortisone acetate, respectively), and Centrum silver and Fludrocortisone acetate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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