Primidone and Cimetidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Primidone (primidone) and Cimetidine (cimetidine). Common drug interactions include bone pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Primidone and Cimetidine. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.



On Jul, 16, 2026

13 people who take Primidone and Cimetidine together, and have interactions are studied.

Primidone and Cimetidine drug interactions.

What are the common drug interactions of Primidone and Cimetidine, by gender? *:

female:

  1. Bone pain
  2. Constipation
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Death
  5. Decreased appetite
  6. Depression
  7. Diarrhoea
  8. Disease progression
  9. Dizziness
  10. Dry mouth

male:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)

What are the common drug interactions of Primidone and Cimetidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Chronic kidney disease
  3. Depression
  4. Renal failure (kidney dysfunction)
  5. Suicidal ideation
  6. Suicide attempt

50-59:

  1. Chronic kidney disease

60+:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Death
  5. Decreased appetite
  6. Diarrhoea
  7. Disease progression
  8. Dizziness
  9. Dry mouth
  10. Dysgeusia (disorder of the sense of taste)

What are the existing conditions these people have? *

  1. Asthma: 7 people, 53.85%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 46.15%
  3. Hypersensitivity: 5 people, 38.46%
  4. High Blood Pressure: 5 people, 38.46%
  5. Depression: 5 people, 38.46%
  6. Parkinson's Disease: 5 people, 38.46%
  7. Cardiac Failure: 5 people, 38.46%
  8. Stress And Anxiety: 5 people, 38.46%
  9. Infection: 4 people, 30.77%
  10. Pain: 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

Do you take Primidone and Cimetidine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Primidone and Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Primidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cimetidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on primidone and cimetidine (the active ingredients of Primidone and Cimetidine, respectively), and Primidone and Cimetidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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