Prinivil and Zegerid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prinivil (lisinopril) and Zegerid (omeprazole; sodium bicarbonate). Common drug interactions include renal failure among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prinivil and Zegerid. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

What is Zegerid?

Zegerid has active ingredients of omeprazole; sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,220 Zegerid users. Check the latest studies of Zegerid.

On Jul, 19, 2026

12 people who take Prinivil and Zegerid together, and have interactions are studied.

What are the common drug interactions of Prinivil and Zegerid, by gender? *:

female:

Renal failure (kidney dysfunction)
Abortion induced (medically referred abortion)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Blood creatine phosphokinase increased
Cystitis interstitial (unknown cause characterized by bladder pain)
Deafness
Dementia (madness)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gout (uric acid crystals building up in the body)

What are the common drug interactions of Prinivil and Zegerid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abortion induced (medically referred abortion)
Anxiety
Deafness
Depression
Disturbance in attention
Facial pain
Headache (pain in head)
Injury
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Jugular vein thrombosis (clot in jugular vein)

30-39:

n/a

40-49:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Fall
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Pain
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Vitamin b12 deficiency

50-59:

Cystitis interstitial (unknown cause characterized by bladder pain)
Dementia (madness)
Fall
Gait disturbance
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Pain in extremity
Renal cyst (kidney cyst)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gout (uric acid crystals building up in the body)

What are the existing conditions these people have? *

Depression: 5 people, 41.67%
Pain: 4 people, 33.33%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 25.00%
Ulcer Haemorrhage (bleeding ulcer): 3 people, 25.00%
Infection: 2 people, 16.67%
Birth Control: 2 people, 16.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 16.67%
Headache (pain in head): 2 people, 16.67%
High Blood Cholesterol: 2 people, 16.67%
Viral Infection: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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