Proamatine and Glucotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proamatine (midodrine hydrochloride) and Glucotrol (glipizide). Common drug interactions include diplegia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Proamatine and Glucotrol. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Glucotrol?

Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.

On Jul, 06, 2026

12 people who take Proamatine and Glucotrol together, and have interactions are studied.

Proamatine and Glucotrol drug interactions.

What are the common drug interactions of Proamatine and Glucotrol, by gender? *:

female:

Diplegia (paralysis of corresponding parts on both sides of the body)
Haemorrhage (bleeding)
Confusional state
Drug hypersensitivity
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Syncope (loss of consciousness with an inability to maintain postural tone)

male:

Chronic kidney disease
Depression
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dizziness (excl vertigo)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Empyema (collection of pus in a cavity in the body)
Fall
Haemorrhage (bleeding)
Hypoaesthesia (reduced sense of touch or sensation)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the common drug interactions of Proamatine and Glucotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Depression
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Death
Nephropathy (damage to or disease of a kidney)
Ataxia (loss of full control of bodily movements)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dizziness (excl vertigo)

50-59:

n/a

60+:

Cardiac arrest
Contusion (a type of hematoma of tissue in which capillaries)
Confusional state
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug hypersensitivity
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 16.67%
Stable Angina (a constant chest pain): 2 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 16.67%
Blood Calcium Increased: 2 people, 16.67%
Cardiac Disorder: 2 people, 16.67%
Cardiac Failure Congestive: 2 people, 16.67%
Depression: 2 people, 16.67%
High Blood Pressure: 2 people, 16.67%
Indigestion: 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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