Profen and Activated charcoal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Activated charcoal (activated charcoal). Common drug interactions include suicidal ideation among females and cognitive disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Activated charcoal. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Activated charcoal?

Activated charcoal has active ingredients of activated charcoal. eHealthMe is studying from 614 Activated charcoal users. Check the latest studies of Activated charcoal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

23 people who take Profen and Activated charcoal together, and have interactions are studied.

Profen and Activated charcoal drug interactions.

What are the common drug interactions of Profen and Activated Charcoal, by gender? *:

female:

Suicidal ideation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Anxiety
Hypersensitivity
Depression
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug ineffective
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Cardiac arrest

male:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Tick-borne fever (fever due to tick bite infection)
Hypersomnia (excessive daytime sleepiness (eds))
Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug toxicity
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Overdose
Agitation (state of anxiety or nervous excitement)
Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)

What are the common drug interactions of Profen and Activated Charcoal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Overdose
Agitation (state of anxiety or nervous excitement)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Oesophageal perforation (hole in oesophagus)
Pneumopericardium (medical condition where air enters the pericardial cavity)
Subcutaneous emphysema (smooth bulging of the skin)
Suicide attempt

20-29:

Tonsillitis (inflammation of tonsil)

30-39:

Completed suicide (act of taking one's own life)
Agitation (state of anxiety or nervous excitement)
Apnoea (suspension of external breathing)
Depressed level of consciousness
Dyskinesia (abnormality or impairment of voluntary movement)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Cardiac arrest
Electrocardiogram qt prolonged
Loss of consciousness
Necrosis ischaemic (death of cell due to lack of blood supply)

40-49:

n/a

50-59:

Alanine aminotransferase increased
Nausea (feeling of having an urge to vomit)
Vomiting
Aspartate aminotransferase increased
Decreased appetite
Diarrhoea
Dizziness
Headache (pain in head)
Injection site pain
Insomnia (sleeplessness)

60+:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 34.78%
Stress And Anxiety: 6 people, 26.09%
Drowsiness: 4 people, 17.39%
Suicide Attempt: 2 people, 8.70%
Cough: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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