Profen and Leqvio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Leqvio (inclisiran sodium). Common drug interactions include haematoma among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Leqvio. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Leqvio?

Leqvio has active ingredients of inclisiran sodium. eHealthMe is studying from 4,052 Leqvio users. Check the latest studies of Leqvio.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

21 people who take Profen and Leqvio together, and have interactions are studied.

What are the common drug interactions of Profen and Leqvio, by gender? *:

female:

Haematoma (collection of blood outside the blood vessels)
Myalgia (muscle pain)
Contusion (a type of hematoma of tissue in which capillaries)
Haemorrhage (bleeding)
Hypersensitivity
Morphoea (a disorder characterized by excessive collagen deposition leading to thickening of skin)
Spinal stenosis (narrowing of spinal column)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Induration (thickening of tissue)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Fatigue (feeling of tiredness)
Retinal vein occlusion (a blockage of the small veins that carry blood away from the retina)
Sensory disturbance (sense disturbance)
Urinary tract infection
Visual acuity reduced (reduced clearness of vision)
Vertigo
Arthralgia (joint pain)
Dysuria (painful or difficult urination)
Injection site erythema (redness at injection site)

What are the common drug interactions of Profen and Leqvio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Peripheral vascular disorder
Retinal vein occlusion (a blockage of the small veins that carry blood away from the retina)
Sensory disturbance (sense disturbance)
Visual acuity reduced (reduced clearness of vision)

50-59:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Fatigue (feeling of tiredness)
Vertigo

60+:

Arthralgia (joint pain)
Myalgia (muscle pain)
Injection site erythema (redness at injection site)
Injection site pain
Pain in extremity
Urinary tract infection
Fatigue (feeling of tiredness)
Gait disturbance
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Neuropathy peripheral (surface nerve damage)

What are the existing conditions these people have? *

Neuralgia (pain in one or more nerves): 15 people, 71.43%
Spinal Stenosis (narrowing of spinal column): 12 people, 57.14%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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