Profen and Oruvail drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Oruvail (ketoprofen). Common drug interactions include abdominal pain among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Oruvail. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Oruvail?

Oruvail has active ingredients of ketoprofen. eHealthMe is studying from 648 Oruvail users. Check the latest studies of Oruvail.

On Jul, 12, 2026

24 people who take Profen and Oruvail together, and have interactions are studied.

What are the common drug interactions of Profen and Oruvail, by gender? *:

female:

Abdominal pain
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
Dyspareunia (painful sexual intercourse)
Muscle spasms (muscle contraction)
Pelvic pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pyrexia (fever)
Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina)
Uterine cancer
Acute sinusitis

male:

Coma (state of unconsciousness lasting more than six hours)
Confusional state
Somnolence (a state of near-sleep, a strong desire for sleep)
Ventricular fibrillation (abnormally irregular heart rhythm)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Viral infection
Weight increased
Abdominal distension
Agitation (state of anxiety or nervous excitement)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

What are the common drug interactions of Profen and Oruvail, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Amblyopia (lazy eye)
Cardiovascular disorder (heart diseases)
Chest pain
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dry mouth
Dyspnoea (difficult or laboured respiration)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

30-39:

Drug addiction

40-49:

Muscle spasms (muscle contraction)
Osteonecrosis of jaw (death of bone of jaw)
Pelvic pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pyrexia (fever)
Rectocele (a bulging of the front wall of the rectum into the back wall of the vagina)
Uterine cancer
Acute sinusitis
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cough

50-59:

Breast cancer
Muscle atrophy (a decrease in the mass of the muscle)

60+:

Bone disorder
Asthenia (weakness)
Breast cancer
Breast cancer metastatic
Cardiac failure congestive
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cervix haemorrhage uterine (bleeding from cervix in birth canal)
Disability
Epicondylitis (tennis elbow)
Fibula fracture

What are the existing conditions these people have? *

Menopausal Symptoms: 2 people, 8.33%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 8.33%
High Blood Pressure: 2 people, 8.33%
Anaemia (lack of blood): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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