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Prolensa and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolensa (bromfenac sodium) and Protonix (pantoprazole sodium). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prolensa and Protonix. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Prolensa?

Prolensa has active ingredients of bromfenac sodium. eHealthMe is studying from 1,170 Prolensa users. Check the latest studies of Prolensa.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 13, 2026

23 people who take Prolensa and Protonix together, and have interactions are studied.

Prolensa and Protonix drug interactions.

What are the common drug interactions of Prolensa and Protonix, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Suicidal ideation
  5. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  6. Depression
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Nephropathy (damage to or disease of a kidney)
  9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  10. Fatigue (feeling of tiredness)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal disorder (kidney disease)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  8. Arthropathy
  9. Bone disorder
  10. Bone erosion

What are the common drug interactions of Prolensa and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Renal injury (kidney injury)
  5. Suicidal ideation
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Depression
  9. Nephropathy (damage to or disease of a kidney)
  10. Renal disorder (kidney disease)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Therapeutic response unexpected
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  5. Renal disorder (kidney disease)
  6. Fatigue (feeling of tiredness)
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Renal injury (kidney injury)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

  1. High Blood Pressure: 12 people, 52.17%
  2. Depression: 11 people, 47.83%
  3. Stress And Anxiety: 11 people, 47.83%
  4. Pain: 11 people, 47.83%
  5. Diabetes: 10 people, 43.48%
  6. High Blood Cholesterol: 9 people, 39.13%
  7. Hypersensitivity: 8 people, 34.78%
  8. Gastric Ulcer (stomach ulcer): 7 people, 30.43%
  9. Asthma: 7 people, 30.43%
  10. Inflammation: 7 people, 30.43%

* Approximation only. Some reports may have incomplete information.

Do you take Prolensa and Protonix?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prolensa and Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prolensa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prolensa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Protonix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bromfenac sodium and pantoprazole sodium (the active ingredients of Prolensa and Protonix, respectively), and Prolensa and Protonix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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