Prolia and Halcion drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prolia (denosumab) and Halcion (triazolam). Common drug interactions include arthralgia among females and blood sodium decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Prolia and Halcion. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,389 Prolia users. Check the latest studies of Prolia.

What is Halcion?

Halcion has active ingredients of triazolam. It is often used in insomnia. eHealthMe is studying from 8,268 Halcion users. Check the latest studies of Halcion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

12 people who take Prolia and Halcion together, and have interactions are studied.

What are the common drug interactions of Prolia and Halcion, by gender? *:

female:

Arthralgia (joint pain)
Pain in extremity
Renal failure (kidney dysfunction)
Retinal toxicity (retina damage due to medication)
Back injury
Chronic kidney disease
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic nephropathy (diabetic kidney disease)
Drug eruption (adverse drug reaction of the skin)

male:

Blood sodium decreased
Decreased appetite
Diarrhoea
Fall
Gait disturbance
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)
Pain in extremity
Urinary tract infection
Weight decreased

What are the common drug interactions of Prolia and Halcion, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Depression
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

60+:

Pain in extremity
Blood sodium decreased
Arthralgia (joint pain)
Retinal toxicity (retina damage due to medication)
Back injury
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic nephropathy (diabetic kidney disease)
Drug eruption (adverse drug reaction of the skin)
Dyspnoea exertional (breathlessness or shortness of breath)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

What are the existing conditions these people have? *

Vulvovaginal Dryness: 2 people, 16.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 16.67%
Thyroid Diseases: 2 people, 16.67%
Sleep Disorder: 2 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Chronic Fatigue Syndrome (disorder that causes extreme fatigue): 2 people, 16.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 16.67%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 16.67%
Neuralgia (pain in one or more nerves): 2 people, 16.67%
Type 2 Diabetes: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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