Promacta and Tenormin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Promacta (eltrombopag olamine) and Tenormin (atenolol). Common drug interactions include bone marrow plasmacyte count increased among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Promacta and Tenormin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Promacta?
Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.
What is Tenormin?
Tenormin has active ingredients of atenolol. It is often used in high blood pressure. eHealthMe is studying from 20,474 Tenormin users. Check the latest studies of Tenormin.
11 people who take Promacta and Tenormin together, and have interactions are studied.

What are the common drug interactions of Promacta and Tenormin, by gender? *:
female:
- Bone marrow plasmacyte count increased
- Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
- Drug ineffective
- Emotional disorder
- Enterocolitis haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Epistaxis (bleed from the nose)
- Gingival bleeding (bleeding gums)
- Hemiparesis (weakness on one side of the body)
- Multiple myeloma (cancer of the plasma cells)
- Neurological symptom (symptoms of nervous system disease)
male:
- Death
- Joint swelling
- Petechiae (a small red or purple spot caused by bleeding into the skin)
- Platelet count decreased
- Pyrexia (fever)
- Oedema peripheral (superficial swelling)
- Swelling face
- Abdominal pain
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
What are the common drug interactions of Promacta and Tenormin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Drug ineffective
- Emotional disorder
- Enterocolitis haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Epistaxis (bleed from the nose)
- Gingival bleeding (bleeding gums)
- Hemiparesis (weakness on one side of the body)
- Neurological symptom (symptoms of nervous system disease)
- Speech disorder
- Antimitochondrial antibody positive
- Biliary cirrhosis primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver)
60+:
- Bone marrow plasmacyte count increased
- Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
- Abdominal pain
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Drug ineffective
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Epistaxis (bleed from the nose)
- Petechiae (a small red or purple spot caused by bleeding into the skin)
- Platelet count decreased
What are the existing conditions these people have? *
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 8 people, 72.73%
- Diabetes: 2 people, 18.18%
- Thrombocytopenia (decrease of platelets in blood): 1 person, 9.09%
- Sneezing: 1 person, 9.09%
- Rhinorrhea (watery mucus discharge from the nose): 1 person, 9.09%
- Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 9.09%
- Neuralgia (pain in one or more nerves): 1 person, 9.09%
- Itching: 1 person, 9.09%
- Hypersensitivity: 1 person, 9.09%
- High Blood Cholesterol: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Promacta and Tenormin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Promacta and Tenormin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Promacta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tenormin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Promacta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tenormin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on eltrombopag olamine and atenolol (the active ingredients of Promacta and Tenormin, respectively), and Promacta and Tenormin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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