Promethazine w/ codeine and Lantus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine w/ codeine (codeine phosphate; promethazine hydrochloride) and Lantus (insulin glargine recombinant). Common drug interactions include hallucination, auditory among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine w/ codeine and Lantus. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine w/ codeine?

Promethazine w/ codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 279 Promethazine w/ codeine users. Check the latest studies of Promethazine w/ codeine.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

On Jul, 20, 2026

30 people who take Promethazine w/ codeine and Lantus together, and have interactions are studied.

Promethazine w/ codeine and Lantus drug interactions.

What are the common drug interactions of Promethazine W/ Codeine and Lantus, by gender? *:

female:

Hallucination, auditory (perceiving sounds without auditory stimulus)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Suicide attempt
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Neuropathy peripheral (surface nerve damage)
Suicidal ideation
Dehydration (dryness resulting from the removal of water)
Hyperglycaemia (high blood sugar)
Loss of consciousness
Pancreatitis (inflammation of pancreas)

male:

Pain in extremity
Arthralgia (joint pain)
Haematuria (presence of blood in urine)
Anaemia (lack of blood)
Osteonecrosis of jaw (death of bone of jaw)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dyspnoea (difficult or laboured respiration)
Injury
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the common drug interactions of Promethazine W/ Codeine and Lantus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dehydration (dryness resulting from the removal of water)
Hyperglycaemia (high blood sugar)
Loss of consciousness
Pancreatitis (inflammation of pancreas)
Renal failure acute (rapid kidney dysfunction)
Abdominal pain
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Neuropathy peripheral (surface nerve damage)

50-59:

Breath odour
Breath sounds
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebral atrophy (decrement in size of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased activity
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea

60+:

Blood uric acid increased
Hyperuricaemia (level of uric acid in the blood that is abnormally high)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 17 people, 56.67%
Multiple Myeloma (cancer of the plasma cells): 9 people, 30.00%
Pain: 8 people, 26.67%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 10.00%
Depression: 3 people, 10.00%
High Blood Pressure: 3 people, 10.00%
Bipolar Disorder (mood disorder): 3 people, 10.00%
Oedema (fluid collection in tissue): 3 people, 10.00%
Insomnia (sleeplessness): 2 people, 6.67%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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