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Vesicare and Osteoporosis - a phase IV clinical study of FDA data

Summary:

Osteoporosis is reported as a side effect among people who take Vesicare (solifenacin succinate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lyrica, and have Hiv infection.

The phase IV clinical study analyzes which people have Osteoporosis when taking Vesicare. It is created by eHealthMe based on reports of 29,875 people who have side effects when taking Vesicare from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.

What is Osteoporosis?

Osteoporosis (bones weak and more likely to break) is found to be associated with 1,811 drugs and 1,902 conditions by eHealthMe. Check the latest studies of Osteoporosis.

On Jul, 20, 2026

29,875 people reported to have side effects when taking Vesicare.
Among them, 94 people (0.31%) have Osteoporosis.

Could Vesicare cause Osteoporosis?

Among these 94 people:

How long have people been on Vesicare when they have Osteoporosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Osteoporosis when taking Vesicare? *

  • female: 81.52 %
  • male: 18.48 %

What is the age of people who have Osteoporosis when taking Vesicare? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.85 %
  • 40-49: 15.38 %
  • 50-59: 38.46 %
  • 60+: 42.31 %

What are other drugs people take besides Vesicare? *

  1. Aspirin: 21 people, 22.34%
  2. Lyrica: 21 people, 22.34%
  3. Clonazepam: 19 people, 20.21%
  4. Nexium: 18 people, 19.15%
  5. Lisinopril: 18 people, 19.15%
  6. Gabapentin: 17 people, 18.09%
  7. Oxycontin: 16 people, 17.02%
  8. Levaquin: 16 people, 17.02%
  9. Hydrochlorothiazide: 15 people, 15.96%
  10. Nystatin: 15 people, 15.96%

What are other side effects people have besides Osteoporosis? *

  1. Depression: 24 people, 25.53%
  2. Pain: 24 people, 25.53%
  3. Stress And Anxiety: 24 people, 25.53%
  4. Urinary Tract Infection: 23 people, 24.47%
  5. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 20 people, 21.28%
  6. Weakness: 20 people, 21.28%
  7. Hip Fracture: 19 people, 20.21%
  8. Intervertebral Disc Protrusion (spinal disc protrusion): 17 people, 18.09%
  9. Fatigue (feeling of tiredness): 17 people, 18.09%
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 17 people, 18.09%

What are the existing conditions these people have? *

  1. Hiv Infection: 15 people, 15.96%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 14.89%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 13.83%
  4. Liver Disorder (liver diseases): 10 people, 10.64%
  5. Neoplasm Malignant (cancer tumour): 10 people, 10.64%
  6. Gastritis (inflammation of stomach): 9 people, 9.57%
  7. Depression: 8 people, 8.51%
  8. High Blood Cholesterol: 8 people, 8.51%
  9. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 7 people, 7.45%
  10. Tinea Infection (fungal skin infection): 7 people, 7.45%

* Approximation only. Some reports may have incomplete information.

Do you take Vesicare and have Osteoporosis?

- Check whether Osteoporosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vesicare:

Osteoporosis treatments and more:

How severe was Osteoporosis and when was it recovered:

Expand to all the drugs that have ingredients of solifenacin succinate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoporosis:

Browse all the conditions that are associated with Osteoporosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on solifenacin succinate (the active ingredients of Vesicare) and Vesicare (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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