Promethazine w/ codeine and Lisinopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine w/ codeine (codeine phosphate; promethazine hydrochloride) and Lisinopril (lisinopril). Common drug interactions include diarrhoea among females and hepatic encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine w/ codeine and Lisinopril. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine w/ codeine?

Promethazine w/ codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 279 Promethazine w/ codeine users. Check the latest studies of Promethazine w/ codeine.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

On Jul, 11, 2026

25 people who take Promethazine w/ codeine and Lisinopril together, and have interactions are studied.

Promethazine w/ codeine and Lisinopril drug interactions.

What are the common drug interactions of Promethazine W/ Codeine and Lisinopril, by gender? *:

female:

Diarrhoea
Eclampsia (acute and life-threatening complication of pregnancy)
Electrocardiogram qt prolonged
Electrocardiogram repolarisation abnormality
Electrocardiogram st-t change
Emotional disorder
Epiglottitis (inflammation of the epiglottis)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Gangrene (body tissue dies)
General physical health deterioration (weak health status)

male:

Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Blood urea increased
Cardiac arrest
Chest pain
Chills (felling of cold)
Confusional state
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hypokalaemia (low potassium)

What are the common drug interactions of Promethazine W/ Codeine and Lisinopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cholecystitis (infection of gallbladder)
Influenza like illness
Insomnia (sleeplessness)
Urinary tract infection
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

30-39:

n/a

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pelvic pain
Chronic kidney disease
Iliac vein occlusion (narrowing of an iliac vein segment between the aortic bifurcation and the groin)

50-59:

Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Chest discomfort
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Colostomy
Connective tissue disorder (any disease that has the connective tissues of the body)
Constipation
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Atelectasis (partial or complete collapse of the lung)
Back pain
Bacterial infection
Balance disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood bicarbonate increased
Blood urea increased
Bradyarrhythmia (heart slowness)

What are the existing conditions these people have? *

Neuralgia (pain in one or more nerves): 6 people, 24.00%
Depression: 6 people, 24.00%
Birth Control: 5 people, 20.00%
Diabetes: 5 people, 20.00%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 5 people, 20.00%
Oedema Peripheral (superficial swelling): 5 people, 20.00%
High Blood Cholesterol: 5 people, 20.00%
Hepatic Neoplasm Malignant (liver cancer): 5 people, 20.00%
Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 5 people, 20.00%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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