Promethazine w/ codeine and Lovenox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine w/ codeine (codeine phosphate; promethazine hydrochloride) and Lovenox (enoxaparin sodium). Common drug interactions include supraventricular tachycardia among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine w/ codeine and Lovenox. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine w/ codeine?

Promethazine w/ codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 279 Promethazine w/ codeine users. Check the latest studies of Promethazine w/ codeine.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.



On Jul, 26, 2026

20 people who take Promethazine w/ codeine and Lovenox together, and have interactions are studied.

Promethazine w/ codeine and Lovenox drug interactions.

What are the common drug interactions of Promethazine W/ Codeine and Lovenox, by gender? *:

female:

  1. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  2. Tuberculin test positive
  3. Uterine cancer
  4. Abdominal pain upper
  5. Atelectasis (partial or complete collapse of the lung)
  6. Back pain
  7. Blood cholesterol increased
  8. Blood glucose increased
  9. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  10. Chest discomfort

male:

  1. Cardiac arrest
  2. Actinomycosis (infection that causes sores, or abscesses)
  3. Cataract (clouding of the lens inside the eye)
  4. Cerebral atrophy (decrement in size of brain)
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Decreased activity
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Diarrhoea
  9. Disease progression
  10. Dysgeusia (disorder of the sense of taste)

What are the common drug interactions of Promethazine W/ Codeine and Lovenox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Insomnia (sleeplessness)
  2. Urinary tract infection
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Cardiomegaly (increased size of heart than normal)
  5. Cardiomyopathy (weakening of the heart muscle)
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Intracardiac thrombus (presence of a circumscribed mass with heart wall)
  8. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
  9. Mass
  10. Multi-organ failure (multisystem organ failure)

30-39:

  1. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  2. Hyperglycaemia (high blood sugar)
  3. Insomnia (sleeplessness)
  4. Sleep disorder
  5. Type 2 diabetes mellitus
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Vision blurred

40-49:

n/a

50-59:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Balance disorder
  4. Blood creatinine increased
  5. Bone disorder
  6. Breath odour
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cardiac arrest
  9. Cataract (clouding of the lens inside the eye)
  10. Cerebral atrophy (decrement in size of brain)

60+:

  1. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  2. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
  3. Cardiac arrest
  4. Chest pain
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
  8. Pneumonia

What are the existing conditions these people have? *

  1. Pain: 10 people, 50.00%
  2. Metastases To Bone (cancer spreads to bone): 9 people, 45.00%
  3. Peripartum Cardiomyopathy (deterioration in cardiac function presenting typically between the last month of pregnancy and up to five months postpartum): 2 people, 10.00%
  4. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 10.00%
  5. Muscle Tightness: 2 people, 10.00%
  6. Depression: 2 people, 10.00%
  7. Sleep Disorder: 1 person, 5.00%
  8. Nausea (feeling of having an urge to vomit): 1 person, 5.00%
  9. Nasal Discharge (discharge from nose): 1 person, 5.00%
  10. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Promethazine w/ codeine and Lovenox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Promethazine w/ codeine and Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Promethazine w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Promethazine w/ codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lovenox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on codeine phosphate; promethazine hydrochloride and enoxaparin sodium (the active ingredients of Promethazine w/ codeine and Lovenox, respectively), and Promethazine w/ codeine and Lovenox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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