Promethazine with codeine and Levaquin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine with codeine (codeine phosphate; promethazine hydrochloride) and Levaquin (levofloxacin). Common drug interactions include chest pain among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine with codeine and Levaquin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine with codeine?

Promethazine with codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. eHealthMe is studying from 269 Promethazine with codeine users. Check the latest studies of Promethazine with codeine.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

On Aug, 12, 2026

11 people who take Promethazine with codeine and Levaquin together, and have interactions are studied.

Promethazine with codeine and Levaquin drug interactions.

What are the common drug interactions of Promethazine With Codeine and Levaquin, by gender? *:

female:

Chest pain
Chronic kidney disease
Abdominal discomfort
Abdominal pain upper
Alanine aminotransferase increased
Arthralgia (joint pain)
Aspartate aminotransferase increased
Back pain
Cardiac failure congestive
Cerumen impaction

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Metastatic malignant melanoma (spreadable cancer tumour of melanine)
Nephrolithiasis (calculi in the kidneys)
Osteomalacia (softening of the bones due to a lack of vitamin d)
Pain
Trigger finger
Bone density decreased
Cataract (clouding of the lens inside the eye)
Chronic kidney disease

What are the common drug interactions of Promethazine With Codeine and Levaquin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Abdominal pain upper
Chest pain
Chills (felling of cold)
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Gastrointestinal inflammation (inflammation of stomach and intestine)
Heart rate increased
Productive cough
Pruritus (severe itching of the skin)

50-59:

Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Aspartate aminotransferase increased
Back pain
Bone density decreased
Cardiac failure congestive
Cerumen impaction
Chest pain

60+:

Cataract (clouding of the lens inside the eye)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dysphagia (a condition in which swallowing is difficult or painful)
Hyperlipidaemia (presence of excess lipids in the blood)
Metastases to lymph nodes (cancer spreads to lymph node)
Metastatic malignant melanoma (spreadable cancer tumour of melanine)
Nephrolithiasis (calculi in the kidneys)
Respiratory tract infection
Trigger finger

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 4 people, 36.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 36.36%
High Blood Pressure: 3 people, 27.27%
Cardiac Disorder: 3 people, 27.27%
Diabetes: 3 people, 27.27%
Hypersensitivity: 3 people, 27.27%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
Asthma: 2 people, 18.18%
Constipation: 2 people, 18.18%
Dry Eyes (lack of adequate tears): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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