Propoxyphene napsylate and acetaminophen and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propoxyphene napsylate and acetaminophen (acetaminophen; propoxyphene napsylate) and Effexor (venlafaxine hydrochloride). Common drug interactions include sensation of foreign body among females and cardiogenic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Propoxyphene napsylate and acetaminophen and Effexor. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Propoxyphene napsylate and acetaminophen?

Propoxyphene napsylate and acetaminophen has active ingredients of acetaminophen; propoxyphene napsylate. It is often used in pain. eHealthMe is studying from 2,057 Propoxyphene napsylate and acetaminophen users. Check the latest studies of Propoxyphene napsylate and acetaminophen.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.



On Jul, 16, 2026

22 people who take Propoxyphene napsylate and acetaminophen and Effexor together, and have interactions are studied.

Propoxyphene napsylate and acetaminophen and Effexor drug interactions.

What are the common drug interactions of Propoxyphene Napsylate And Acetaminophen and Effexor, by gender? *:

female:

  1. Sensation of foreign body
  2. Tinnitus (a ringing in the ears)
  3. Cataract (clouding of the lens inside the eye)
  4. Dizziness
  5. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  6. Laryngitis (inflammation of the larynx)
  7. Spinal osteoarthritis (joint cartilage loss in spine)
  8. Balance disorder
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Neck pain

male:

  1. Cardiogenic shock (inadequate circulation of blood)
  2. Hypotension (abnormally low blood pressure)
  3. Overdose

What are the common drug interactions of Propoxyphene Napsylate And Acetaminophen and Effexor, by age (0-1 to 60+)? *:

0-1:

  1. Chest pain
  2. Nephrolithiasis (calculi in the kidneys)
  3. Pericardial effusion (fluid around the heart)
  4. Pulmonary hypertension (increase in blood pressure in the lung artery)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Type 2 diabetes mellitus
  7. Urinary tract infection

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abscess (pus)
  2. Cough
  3. Delusion (a false belief or opinion)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Eye pain
  6. Folliculitis (infection of hair root)
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Pelvic pain

40-49:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  3. Blindness
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Femoral arterial stenosis (narrowing of artery of femur bone)
  8. Obesity (having too much body fat)
  9. Oedema (fluid collection in tissue)
  10. Oedema peripheral (superficial swelling)

50-59:

  1. Abnormal sleep-related event
  2. Depressed level of consciousness
  3. Fatigue (feeling of tiredness)
  4. Respiratory rate decreased (less breathing rate/min)

60+:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Tardive dyskinesia (a disorder that involves involuntary movements)
  3. Dizziness
  4. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  5. Laryngitis (inflammation of the larynx)
  6. Spinal osteoarthritis (joint cartilage loss in spine)
  7. Balance disorder
  8. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  9. Neck pain
  10. Postnasal drip

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 50.00%
  2. Sleep Disorder: 2 people, 9.09%
  3. Menstruation Irregular: 2 people, 9.09%
  4. Itching: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Propoxyphene napsylate and acetaminophen and Effexor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Propoxyphene napsylate and acetaminophen and Effexor:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propoxyphene napsylate and acetaminophen:

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Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propoxyphene napsylate and acetaminophen and drugs from A to Z:

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Browse all interactions between Effexor and drugs from A to Z:

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How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; propoxyphene napsylate and venlafaxine hydrochloride (the active ingredients of Propoxyphene napsylate and acetaminophen and Effexor, respectively), and Propoxyphene napsylate and acetaminophen and Effexor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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