Propulsid and Lamictal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Propulsid (cisapride monohydrate) and Lamictal (lamotrigine). Common drug interactions include dystonia among females and status epilepticus among males.
The phase IV clinical study analyzes what interactions people have when they take Propulsid and Lamictal. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Propulsid?
Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.
What is Lamictal?
Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.
13 people who take Propulsid and Lamictal together, and have interactions are studied.

What are the common drug interactions of Propulsid and Lamictal, by gender? *:
female:
- Dystonia (abnormal muscle tone)
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Vomiting
- Arrhythmia (irregular heartbeat)
- Ataxia (loss of full control of bodily movements)
- Vertigo
male:
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
- Apnoea (suspension of external breathing)
- Laceration (tearing of soft body tissue)
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Platelet count decreased
- Pulmonary oedema (fluid accumulation in the lungs)
- Pyrexia (fever)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Respiratory rate increased (excess breathing rate/min)
- Asthma
What are the common drug interactions of Propulsid and Lamictal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Dystonia (abnormal muscle tone)
- Vomiting
10-19:
- Apnoea (suspension of external breathing)
- Arrhythmia (irregular heartbeat)
- Cardiac arrest
- Pyrexia (fever)
- Respiratory rate increased (excess breathing rate/min)
20-29:
- Pulmonary oedema (fluid accumulation in the lungs)
- Asthma
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Cryptogenic organizing pneumonia (small airways (bronchioles) and air exchange sac (alveoli) become inflamed with connective tissue)
- Granuloma (a small area of inflammation due to tissue injury)
- Hypoxia (low oxygen in tissues)
- Interstitial lung disease
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
30-39:
- Dystonia (abnormal muscle tone)
40-49:
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
50-59:
- Platelet count decreased
60+:
n/a
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Propulsid and Lamictal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Propulsid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lamictal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Propulsid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamictal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisapride monohydrate and lamotrigine (the active ingredients of Propulsid and Lamictal, respectively), and Propulsid and Lamictal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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