Pulmicort and Arava drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pulmicort (budesonide) and Arava (leflunomide). Common drug interactions include drug hypersensitivity among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Pulmicort and Arava. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Pulmicort?

Pulmicort has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 34,980 Pulmicort users. Check the latest studies of Pulmicort.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

On Jul, 12, 2026

86 people who take Pulmicort and Arava together, and have interactions are studied.

What are the common drug interactions of Pulmicort and Arava, by gender? *:

female:

Drug hypersensitivity
Fatigue (feeling of tiredness)
Gingival cancer (cancer of gums)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Neoplasm malignant (cancer tumour)
Nephrolithiasis (calculi in the kidneys)
Insomnia (sleeplessness)
Pyrexia (fever)
Back pain
Fungal infection

male:

Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Acne (skin problems that cause pimples)
Acute respiratory distress syndrome
Aortic valve incompetence
Aortic valve replacement
Apnoea (suspension of external breathing)
Arrhythmia (irregular heartbeat)
Ataxia (loss of full control of bodily movements)
Atrioventricular block complete (heart block complete)

What are the common drug interactions of Pulmicort and Arava, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Kidney infection
Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

Abdominal sepsis (abdominal infection)
Acute respiratory distress syndrome
Asthenia (weakness)
Asthmatic crisis
Blood creatine phosphokinase increased
C-reactive protein increased
Chest pain
Death
Drug exposure during pregnancy
Drug ineffective

30-39:

Sinusitis (inflammation of sinus)
Drug exposure during pregnancy
Oxygen consumption decreased
Prolonged labour
Adverse event
Cardiac failure
Chest pain
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Interstitial lung disease

40-49:

Colitis (inflammation of colon)
Hypertension (high blood pressure)
Irritable bowel syndrome
Nausea (feeling of having an urge to vomit)
Oral candidiasis (fungal infection of mouth)
White blood cell count decreased
Headache (pain in head)

50-59:

Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Malaise (a feeling of general discomfort or uneasiness)
Neoplasm malignant (cancer tumour)
Nephrolithiasis (calculi in the kidneys)
Fatigue (feeling of tiredness)
Nasopharyngitis (inflammation of the nasopharynx)
Fall
Fungal infection
Insomnia (sleeplessness)
Urethritis (inflammation of the urethra)

60+:

Arthralgia (joint pain)
Fall
Localised infection (infection at the single location)
Nasopharyngitis (inflammation of the nasopharynx)
Oral infection
Poor venous access
Procedural pain
Stomatitis (inflammation of mucous membrane of mouth)
Tooth disorder (tooth disease)
Urinary retention (the inability to completely or partially empty the bladder)

What are the existing conditions these people have? *

Sinus Congestion (blockage of sinus): 9 people, 10.47%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 6.98%
Hypersensitivity: 5 people, 5.81%

* Approximation only. Some reports may have incomplete information.

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