Quinine and Dexamethasone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Quinine (cinchona) and Dexamethasone (dexamethasone). Common drug interactions include sinusitis among females and joint swelling among males.
The phase IV clinical study analyzes what interactions people have when they take Quinine and Dexamethasone. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.
What is Quinine?
Quinine has active ingredients of cinchona. It is often used in leg pain. eHealthMe is studying from 4,981 Quinine users. Check the latest studies of Quinine.
What is Dexamethasone?
Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.
97 people who take Quinine and Dexamethasone together, and have interactions are studied.

What are the common drug interactions of Quinine and Dexamethasone, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Bone pain
- Oedema peripheral (superficial swelling)
- Vomiting
- Abdominal pain lower
- Acute respiratory failure
- Anal fissure
- Neuropathy peripheral (surface nerve damage)
- Constipation
- Diarrhoea
male:
- Joint swelling
- Choroidal effusion (fluid collection in vascular layer of eye that nourishes retina)
- Cellulitis (infection under the skin)
- Drug hypersensitivity
- Infection
- Osteonecrosis (death of bone)
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
- Pericarditis (inflammation of the pericardium)
- Eye swelling
- Infusion related reaction
What are the common drug interactions of Quinine and Dexamethasone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Drug hypersensitivity
20-29:
n/a
30-39:
- Abdominal pain upper
- Alanine aminotransferase increased
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Blood chloride decreased
- Blood cholesterol increased
- Blood creatinine increased
- Blood sodium decreased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Asthenia (weakness)
- Deformity (disfigurement)
- Dental caries
- Discomfort
- Eating disorder
- Emotional distress
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gingivitis (inflammation of gums)
50-59:
- Depressed mood
- Dizziness
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Lacrimation increased
- Left ventricular dysfunction
- Mucosal inflammation (infection of mucous membrane)
- Muscle spasms (muscle contraction)
- Nail disorder (disease of nail)
- Nail infection
- Nasopharyngitis (inflammation of the nasopharynx)
60+:
- Constipation
- Abdominal pain upper
- Cataract (clouding of the lens inside the eye)
- Vulvovaginal mycotic infection (vulvovaginal fungal infection)
- Drug ineffective
- Pneumonia
- Blood pressure increased
- Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Pain in extremity
What are the existing conditions these people have? *
- Muscle Spasms (muscle contraction): 59 people, 60.82%
- Blood Glucose Increased: 37 people, 38.14%
- Diabetes: 35 people, 36.08%
- Pain: 14 people, 14.43%
- Nausea (feeling of having an urge to vomit): 12 people, 12.37%
- Breast Cancer: 11 people, 11.34%
- Insomnia (sleeplessness): 10 people, 10.31%
- Constipation: 9 people, 9.28%
- Depression: 9 people, 9.28%
- Cough: 8 people, 8.25%
* Approximation only. Some reports may have incomplete information.
Do you take Quinine and Dexamethasone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Quinine (4,981 reports)
- Dexamethasone (161,927 reports)
Browse all drug interactions of Quinine and Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Quinine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Quinine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexamethasone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on cinchona and dexamethasone (the active ingredients of Quinine and Dexamethasone, respectively), and Quinine and Dexamethasone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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