Rapaflo and Otezla drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rapaflo (silodosin) and Otezla (apremilast). Common drug interactions include death among males.
The phase IV clinical study analyzes what interactions people have when they take Rapaflo and Otezla. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Rapaflo?
Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.
What is Otezla?
Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.
12 people who take Rapaflo and Otezla together, and have interactions are studied.
What are the common drug interactions of Rapaflo and Otezla, by gender? *:
female:
n/a
male:
- Death
- Nausea (feeling of having an urge to vomit)
- Dysuria (painful or difficult urination)
- Flatulence (flatus expelled through the anus)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Pruritus (severe itching of the skin)
- Psoriasis (immune-mediated disease that affects the skin)
- Skin exfoliation (removal of the oldest dead skin cells)
- Suicidal ideation
- Vomiting
What are the common drug interactions of Rapaflo and Otezla, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal distension
- Flatulence (flatus expelled through the anus)
- Nausea (feeling of having an urge to vomit)
- Vomiting
30-39:
n/a
40-49:
n/a
50-59:
- Psoriasis (immune-mediated disease that affects the skin)
60+:
- Death
- Diarrhoea
- Suicidal ideation
- Weight decreased
- Headache (pain in head)
- Abdominal pain upper
- Asthenia (weakness)
- Decreased appetite
- Depressed mood
- Dysuria (painful or difficult urination)
What are the existing conditions these people have? *
- Psoriasis (immune-mediated disease that affects the skin): 10 people, 83.33%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
- Prostatomegaly (enlargement of the prostate): 1 person, 8.33%
- Prostatic Disorder: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Rapaflo and Otezla?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rapaflo and Otezla:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rapaflo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Otezla:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rapaflo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Otezla and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on silodosin and apremilast (the active ingredients of Rapaflo and Otezla, respectively), and Rapaflo and Otezla (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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