Reclast and Imdur drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Reclast (zoledronic acid) and Imdur (isosorbide mononitrate). Common drug interactions include sinusitis among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Reclast and Imdur. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Reclast?
Reclast has active ingredients of zoledronic acid. It is often used in osteoporosis. eHealthMe is studying from 15,774 Reclast users. Check the latest studies of Reclast.
What is Imdur?
Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.
25 people who take Reclast and Imdur together, and have interactions are studied.

What are the common drug interactions of Reclast and Imdur, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Weight decreased
- Abasia (inability to walk)
- Arthropathy
- Femur fracture
- Food intolerance (inability to have food)
- Infection
- Localised infection (infection at the single location)
- Nausea (feeling of having an urge to vomit)
- Rash
male:
- Pyrexia (fever)
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Cataract (clouding of the lens inside the eye)
- Depression
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Glaucoma (increased fluid pressure in the eye with vision loss)
- Immune system disorder
- Lung disorder (lung disease)
What are the common drug interactions of Reclast and Imdur, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
- Atrioventricular block complete (heart block complete)
- Cardiac disorder
- Cardiac failure chronic
- Carotid artery disease
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dehydration (dryness resulting from the removal of water)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypercholesterolaemia (high levels of cholesterol in the blood)
50-59:
- Lung disorder (lung disease)
- Lung infection
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Nerve compression
- Pain
- Pneumonia
- Psoriasis (immune-mediated disease that affects the skin)
- Pyrexia (fever)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
60+:
- Diarrhoea
- Discomfort
- Abasia (inability to walk)
- Arthropathy
- Blood creatinine increased
- Femur fracture
- Localised infection (infection at the single location)
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Peripheral swelling
What are the existing conditions these people have? *
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 16.00%
- Nausea (feeling of having an urge to vomit): 4 people, 16.00%
- High Blood Pressure: 4 people, 16.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
- Diarrhea: 4 people, 16.00%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 16.00%
- Cardiac Disorder: 4 people, 16.00%
- Asthma: 4 people, 16.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 12.00%
- High Blood Cholesterol: 3 people, 12.00%
* Approximation only. Some reports may have incomplete information.
Do you take Reclast and Imdur?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Reclast and Imdur:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Reclast:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Imdur:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reclast and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Imdur and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid and isosorbide mononitrate (the active ingredients of Reclast and Imdur, respectively), and Reclast and Imdur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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