Relistor and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Relistor (methylnaltrexone bromide) and Ms contin (morphine sulfate). Common drug interactions include constipation among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Relistor and Ms contin. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Relistor?

Relistor has active ingredients of methylnaltrexone bromide. eHealthMe is studying from 1,659 Relistor users. Check the latest studies of Relistor.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.



On Jul, 10, 2026

30 people who take Relistor and Ms contin together, and have interactions are studied.

Relistor and Ms contin drug interactions.

What are the common drug interactions of Relistor and Ms Contin, by gender? *:

female:

  1. Constipation
  2. Death
  3. Depressed level of consciousness
  4. Drug effect decreased
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Eye pruritus (eye itching)
  7. Flatulence (flatus expelled through the anus)
  8. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  9. Lacrimation increased
  10. Lethargy (tiredness)

male:

  1. Constipation
  2. Abdominal pain
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Bacteraemia (presence of bacteria in the blood)
  5. Cardiac arrest
  6. Cardiac failure congestive
  7. Chest pain
  8. Coma (state of unconsciousness lasting more than six hours)
  9. Depression
  10. Disability

What are the common drug interactions of Relistor and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cerebrospinal fluid leakage
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Pseudomeningocele (abnormal collection of cerebrospinal fluid)
  4. Swelling

30-39:

n/a

40-49:

n/a

50-59:

  1. Migraine (headache)
  2. Vomiting
  3. Drug ineffective
  4. Hangover
  5. Abdominal pain
  6. Muscle tightness
  7. Muscular weakness (muscle weakness)
  8. Oral disorder (mouth disease)
  9. Lipoma (a growth of fatty tissue that slowly develops just under your skin)
  10. Abdominal discomfort

60+:

  1. Constipation
  2. Faecaloma (hard mass of fecal matter)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Bacteraemia (presence of bacteria in the blood)
  5. Blood creatinine increased
  6. Cardiac arrest
  7. Cardiac failure congestive
  8. Coma (state of unconsciousness lasting more than six hours)
  9. Depressed level of consciousness
  10. Drug effect decreased

What are the existing conditions these people have? *

  1. Constipation: 16 people, 53.33%
  2. Stress And Anxiety: 6 people, 20.00%
  3. Muscle Spasms (muscle contraction): 5 people, 16.67%
  4. Nausea (feeling of having an urge to vomit): 4 people, 13.33%
  5. Mood Swings (an extreme or rapid change in mood): 4 people, 13.33%
  6. Migraine (headache): 4 people, 13.33%
  7. Immunodeficiency Common Variable: 4 people, 13.33%
  8. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 13.33%
  9. Spinal Pain (pain in spine): 3 people, 10.00%
  10. Nerve Injury: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Relistor and Ms contin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Relistor and Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Relistor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Relistor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methylnaltrexone bromide and morphine sulfate (the active ingredients of Relistor and Ms contin, respectively), and Relistor and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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