Requip and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Requip (ropinirole hydrochloride) and Cyclophosphamide (cyclophosphamide). Common drug interactions include gait disturbance among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Requip and Cyclophosphamide. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

On Jul, 12, 2026

64 people who take Requip and Cyclophosphamide together, and have interactions are studied.

Requip and Cyclophosphamide drug interactions.

What are the common drug interactions of Requip and Cyclophosphamide, by gender? *:

female:

Gait disturbance
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Blood pressure increased
Cardiomegaly (increased size of heart than normal)
Chest pain
Muscle spasms (muscle contraction)

male:

Anaemia (lack of blood)
Cataract (clouding of the lens inside the eye)
Constipation
Tooth abscess (pus formation in tooth)
Atelectasis (partial or complete collapse of the lung)
Cardiac failure congestive
Chest discomfort
Cough
Deformity (disfigurement)
Dental caries

What are the common drug interactions of Requip and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Atrioventricular block first degree (heart block first degree)
Bone loss
Bradycardia (abnormally slow heart action)
Cardiomegaly (increased size of heart than normal)
Cataract (clouding of the lens inside the eye)

40-49:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Cardiomegaly (increased size of heart than normal)
Coronary artery stenosis (narrowing of coronary artery)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall
Fatigue (feeling of tiredness)
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Pulmonary embolism (blockage of the main artery of the lung)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tongue disorder (disease of tongue)

50-59:

Dystonia (abnormal muscle tone)
Fall
Fracture nonunion (permanent failure of healing following a broken bone)
Gait disturbance
Hair colour changes
Heart rate increased
Hyperreflexia (overactive or over responsive reflexes)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)

60+:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Cataract (clouding of the lens inside the eye)
Haematuria (presence of blood in urine)
Hypersomnia (excessive daytime sleepiness (eds))
Malaise (a feeling of general discomfort or uneasiness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Metastases to bone (cancer spreads to bone)
Metastases to skin (cancer spreads to skin)
Osteoporosis (bones weak and more likely to break)
Pain

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 12 people, 18.75%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 17.19%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 17.19%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 6.25%
Nausea (feeling of having an urge to vomit): 4 people, 6.25%
Drowsiness: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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